a tool for identifying drug-targetable redox-active disulphides

Tumor necrosis factor ligand superfamily member 6

Intramolecular

Cysteine 202 and cysteine 233

A redox-regulated disulphide may form within Tumor necrosis factor ligand superfamily member 6 between cysteines 202 and 233.

Details

Redox score ?

89

PDB code

Structure name

crystal structure of fasl and dcr3 complex

Structure deposition date

2013-09-18

Thiol separation (Å)

2

Half-sphere exposure sum ?

46

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

202

Residue number B

233

Peptide name

Tumor necrosis factor ligand superfamily member 6

Ligandability

Cysteine 202 of Tumor necrosis factor ligand superfamily member 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 233 of Tumor necrosis factor ligand superfamily member 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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