LIM and senescent cell antigen-like-containing domain protein 1
Intramolecular
Cysteine 10 and cysteine 13
Cysteine 161 and cysteine 164
Cysteine 38 and cysteine 59
Cysteine 219 and cysteine 222
Cysteine 161 and cysteine 184
Cysteine 219 and cysteine 240
Cysteine 97 and cysteine 100
Cysteine 193 and cysteine 196
Cysteine 161 and cysteine 181
Cysteine 71 and cysteine 74
More...Cysteine 97 and cysteine 121
Cysteine 97 and cysteine 118
Cysteine 71 and cysteine 94
Cysteine 135 and cysteine 138
Cysteine 252 and cysteine 272
Cysteine 222 and cysteine 240
Cysteine 252 and cysteine 255
Cysteine 118 and cysteine 121
Cysteine 100 and cysteine 118
Cysteine 164 and cysteine 184
Cysteine 252 and cysteine 275
Cysteine 164 and cysteine 181
Cysteine 181 and cysteine 184
Cysteine 13 and cysteine 35
Cysteine 255 and cysteine 275
Cysteine 74 and cysteine 94
Cysteine 100 and cysteine 121
Cysteine 281 and cysteine 303
Cysteine 278 and cysteine 281
Cysteine 255 and cysteine 272
Cysteine 281 and cysteine 300
Cysteine 278 and cysteine 300
Cysteine 272 and cysteine 275
Cysteine 300 and cysteine 303
Cysteine 41 and cysteine 59
Cysteine 10 and cysteine 35
Cysteine 278 and cysteine 303
Cysteine 38 and cysteine 41
4hi8 B 10 B 13
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 10 and 13.
Details
Redox score ?
94
PDB code
4hi8
Structure name
structure of integrin-linked kinase ankyrin repeat domain in complex with pinch1 lim1 domain collected at high energy, wavelength 0
Structure deposition date
2012-10-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
54
Minimum pKa ?
0
% buried
47
Peptide accession
P48059
Residue number A
10
Residue number B
13
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 10 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 13 of LIM and senescent cell antigen-like-containing domain protein 1
2cor A 44 A 47
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 161 and 164 (44 and 47 respectively in this structure).
Details
Redox score ?
92
PDB code
2cor
Structure name
solution structure of the third lim domain of particularly interesting new cys-his protein
Structure deposition date
2005-05-18
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
4
% buried
0
Peptide accession
P48059
Residue number A
161
Residue number B
164
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 161 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 164 of LIM and senescent cell antigen-like-containing domain protein 1
4hi8 B 38 B 59
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 38 and 59.
Details
Redox score ?
91
PDB code
4hi8
Structure name
structure of integrin-linked kinase ankyrin repeat domain in complex with pinch1 lim1 domain collected at high energy, wavelength 0
Structure deposition date
2012-10-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
0
% buried
70
Peptide accession
P48059
Residue number A
38
Residue number B
59
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 38 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 59 of LIM and senescent cell antigen-like-containing domain protein 1
7lt9 B 219 B 222
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 219 and 222.
Details
Redox score ?
91
PDB code
7lt9
Structure name
crystal structure of ras suppressor-1 in complex with pinch-1 lim4-5 domains
Structure deposition date
2021-02-19
Thiol separation (Å)
3
Half-sphere exposure sum ?
44
Minimum pKa ?
5
% buried
3
Peptide accession
P48059
Residue number A
219
Residue number B
222
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 219 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 222 of LIM and senescent cell antigen-like-containing domain protein 1
2cor A 44 A 67
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 161 and 184 (44 and 67 respectively in this structure).
Details
Redox score ?
90
PDB code
2cor
Structure name
solution structure of the third lim domain of particularly interesting new cys-his protein
Structure deposition date
2005-05-18
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
4
% buried
0
Peptide accession
P48059
Residue number A
161
Residue number B
184
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 161 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 184 of LIM and senescent cell antigen-like-containing domain protein 1
7lt9 B 219 B 240
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 219 and 240.
Details
Redox score ?
89
PDB code
7lt9
Structure name
crystal structure of ras suppressor-1 in complex with pinch-1 lim4-5 domains
Structure deposition date
2021-02-19
Thiol separation (Å)
3
Half-sphere exposure sum ?
56
Minimum pKa ?
5
% buried
3
Peptide accession
P48059
Residue number A
219
Residue number B
240
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 219 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 240 of LIM and senescent cell antigen-like-containing domain protein 1
2d8x A 34 A 37
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 97 and 100 (34 and 37 respectively in this structure).
Details
Redox score ?
89
PDB code
2d8x
Structure name
solution structure of the second lim domain of particularly interesting new cys-his protein (pinch)
Structure deposition date
2005-12-08
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
5
% buried
4
Peptide accession
P48059
Residue number A
97
Residue number B
100
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 97 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 100 of LIM and senescent cell antigen-like-containing domain protein 1
7d2t B 193 B 196
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 193 and 196.
Details
Redox score ?
89
PDB code
7d2t
Structure name
crystal structure of rsu1/pinch1_lim45c complex
Structure deposition date
2020-09-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
42
Minimum pKa ?
5
% buried
7
Peptide accession
P48059
Residue number A
193
Residue number B
196
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 193 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 196 of LIM and senescent cell antigen-like-containing domain protein 1
2cor A 44 A 64
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 161 and 181 (44 and 64 respectively in this structure).
Details
Redox score ?
89
PDB code
2cor
Structure name
solution structure of the third lim domain of particularly interesting new cys-his protein
Structure deposition date
2005-05-18
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
4
% buried
0
Peptide accession
P48059
Residue number A
161
Residue number B
181
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 161 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 181 of LIM and senescent cell antigen-like-containing domain protein 1
2d8x A 8 A 11
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 71 and 74 (8 and 11 respectively in this structure).
Details
Redox score ?
88
PDB code
2d8x
Structure name
solution structure of the second lim domain of particularly interesting new cys-his protein (pinch)
Structure deposition date
2005-12-08
Thiol separation (Å)
4
Half-sphere exposure sum ?
43
Minimum pKa ?
5
% buried
2
Peptide accession
P48059
Residue number A
71
Residue number B
74
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 71 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 74 of LIM and senescent cell antigen-like-containing domain protein 1
2d8x A 34 A 58
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 97 and 121 (34 and 58 respectively in this structure).
Details
Redox score ?
88
PDB code
2d8x
Structure name
solution structure of the second lim domain of particularly interesting new cys-his protein (pinch)
Structure deposition date
2005-12-08
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
5
% buried
4
Peptide accession
P48059
Residue number A
97
Residue number B
121
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 97 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 121 of LIM and senescent cell antigen-like-containing domain protein 1
2d8x A 34 A 55
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 97 and 118 (34 and 55 respectively in this structure).
Details
Redox score ?
87
PDB code
2d8x
Structure name
solution structure of the second lim domain of particularly interesting new cys-his protein (pinch)
Structure deposition date
2005-12-08
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
5
% buried
4
Peptide accession
P48059
Residue number A
97
Residue number B
118
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 97 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 118 of LIM and senescent cell antigen-like-containing domain protein 1
2d8x A 8 A 31
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 71 and 94 (8 and 31 respectively in this structure).
Details
Redox score ?
85
PDB code
2d8x
Structure name
solution structure of the second lim domain of particularly interesting new cys-his protein (pinch)
Structure deposition date
2005-12-08
Thiol separation (Å)
4
Half-sphere exposure sum ?
56
Minimum pKa ?
5
% buried
4
Peptide accession
P48059
Residue number A
71
Residue number B
94
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 71 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 94 of LIM and senescent cell antigen-like-containing domain protein 1
2cor A 18 A 21
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 135 and 138 (18 and 21 respectively in this structure).
Details
Redox score ?
85
PDB code
2cor
Structure name
solution structure of the third lim domain of particularly interesting new cys-his protein
Structure deposition date
2005-05-18
Thiol separation (Å)
4
Half-sphere exposure sum ?
41
Minimum pKa ?
7
% buried
2
Peptide accession
P48059
Residue number A
135
Residue number B
138
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 135 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 138 of LIM and senescent cell antigen-like-containing domain protein 1
7lt9 B 252 B 272
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 252 and 272.
Details
Redox score ?
85
PDB code
7lt9
Structure name
crystal structure of ras suppressor-1 in complex with pinch-1 lim4-5 domains
Structure deposition date
2021-02-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
58
Minimum pKa ?
6
% buried
27
Peptide accession
P48059
Residue number A
252
Residue number B
272
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 252 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 272 of LIM and senescent cell antigen-like-containing domain protein 1
7d2u B 222 B 240
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 222 and 240.
Details
Redox score ?
84
PDB code
7d2u
Structure name
crystal structure of rsu1/pinch1_lim45c complex
Structure deposition date
2020-09-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
5
% buried
0
Peptide accession
P48059
Residue number A
222
Residue number B
240
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 222 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 240 of LIM and senescent cell antigen-like-containing domain protein 1
7d2t D 252 D 255
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 252 and 255.
Details
Redox score ?
82
PDB code
7d2t
Structure name
crystal structure of rsu1/pinch1_lim45c complex
Structure deposition date
2020-09-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
6
% buried
39
Peptide accession
P48059
Residue number A
252
Residue number B
255
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 252 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 255 of LIM and senescent cell antigen-like-containing domain protein 1
2d8x A 55 A 58
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 118 and 121 (55 and 58 respectively in this structure).
Details
Redox score ?
81
PDB code
2d8x
Structure name
solution structure of the second lim domain of particularly interesting new cys-his protein (pinch)
Structure deposition date
2005-12-08
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
8
% buried
0
Peptide accession
P48059
Residue number A
118
Residue number B
121
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 118 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 121 of LIM and senescent cell antigen-like-containing domain protein 1
2d8x A 37 A 55
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 100 and 118 (37 and 55 respectively in this structure).
Details
Redox score ?
81
PDB code
2d8x
Structure name
solution structure of the second lim domain of particularly interesting new cys-his protein (pinch)
Structure deposition date
2005-12-08
Thiol separation (Å)
4
Half-sphere exposure sum ?
46
Minimum pKa ?
8
% buried
0
Peptide accession
P48059
Residue number A
100
Residue number B
118
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 100 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 118 of LIM and senescent cell antigen-like-containing domain protein 1
2cor A 47 A 67
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 164 and 184 (47 and 67 respectively in this structure).
Details
Redox score ?
80
PDB code
2cor
Structure name
solution structure of the third lim domain of particularly interesting new cys-his protein
Structure deposition date
2005-05-18
Thiol separation (Å)
4
Half-sphere exposure sum ?
41
Minimum pKa ?
8
% buried
0
Peptide accession
P48059
Residue number A
164
Residue number B
184
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 164 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 184 of LIM and senescent cell antigen-like-containing domain protein 1
7d2t D 252 D 275
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 252 and 275.
Details
Redox score ?
79
PDB code
7d2t
Structure name
crystal structure of rsu1/pinch1_lim45c complex
Structure deposition date
2020-09-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
8
% buried
41
Peptide accession
P48059
Residue number A
252
Residue number B
275
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 252 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 275 of LIM and senescent cell antigen-like-containing domain protein 1
2cor A 47 A 64
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 164 and 181 (47 and 64 respectively in this structure).
Details
Redox score ?
77
PDB code
2cor
Structure name
solution structure of the third lim domain of particularly interesting new cys-his protein
Structure deposition date
2005-05-18
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
9
% buried
0
Peptide accession
P48059
Residue number A
164
Residue number B
181
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 164 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 181 of LIM and senescent cell antigen-like-containing domain protein 1
2cor A 64 A 67
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 181 and 184 (64 and 67 respectively in this structure).
Details
Redox score ?
77
PDB code
2cor
Structure name
solution structure of the third lim domain of particularly interesting new cys-his protein
Structure deposition date
2005-05-18
Thiol separation (Å)
4
Half-sphere exposure sum ?
54
Minimum pKa ?
8
% buried
0
Peptide accession
P48059
Residue number A
181
Residue number B
184
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 181 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 184 of LIM and senescent cell antigen-like-containing domain protein 1
4hi8 B 13 B 35
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 13 and 35.
Details
Redox score ?
77
PDB code
4hi8
Structure name
structure of integrin-linked kinase ankyrin repeat domain in complex with pinch1 lim1 domain collected at high energy, wavelength 0
Structure deposition date
2012-10-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
67
Minimum pKa ?
7
% buried
57
Peptide accession
P48059
Residue number A
13
Residue number B
35
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 13 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 35 of LIM and senescent cell antigen-like-containing domain protein 1
7lt9 B 255 B 275
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 255 and 275.
Details
Redox score ?
76
PDB code
7lt9
Structure name
crystal structure of ras suppressor-1 in complex with pinch-1 lim4-5 domains
Structure deposition date
2021-02-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
8
% buried
28
Peptide accession
P48059
Residue number A
255
Residue number B
275
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 255 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 275 of LIM and senescent cell antigen-like-containing domain protein 1
2d8x A 11 A 31
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 74 and 94 (11 and 31 respectively in this structure).
Details
Redox score ?
76
PDB code
2d8x
Structure name
solution structure of the second lim domain of particularly interesting new cys-his protein (pinch)
Structure deposition date
2005-12-08
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
9
% buried
2
Peptide accession
P48059
Residue number A
74
Residue number B
94
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 74 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 94 of LIM and senescent cell antigen-like-containing domain protein 1
2d8x A 37 A 58
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 100 and 121 (37 and 58 respectively in this structure).
Details
Redox score ?
76
PDB code
2d8x
Structure name
solution structure of the second lim domain of particularly interesting new cys-his protein (pinch)
Structure deposition date
2005-12-08
Thiol separation (Å)
4
Half-sphere exposure sum ?
41
Minimum pKa ?
11
% buried
0
Peptide accession
P48059
Residue number A
100
Residue number B
121
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 100 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 121 of LIM and senescent cell antigen-like-containing domain protein 1
7lt9 B 281 B 303
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 281 and 303.
Details
Redox score ?
75
PDB code
7lt9
Structure name
crystal structure of ras suppressor-1 in complex with pinch-1 lim4-5 domains
Structure deposition date
2021-02-19
Thiol separation (Å)
3
Half-sphere exposure sum ?
67
Minimum pKa ?
9
% buried
64
Peptide accession
P48059
Residue number A
281
Residue number B
303
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 281 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 303 of LIM and senescent cell antigen-like-containing domain protein 1
7lt9 B 278 B 281
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 278 and 281.
Details
Redox score ?
75
PDB code
7lt9
Structure name
crystal structure of ras suppressor-1 in complex with pinch-1 lim4-5 domains
Structure deposition date
2021-02-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
71
Minimum pKa ?
9
% buried
nan
Peptide accession
P48059
Residue number A
278
Residue number B
281
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 278 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 281 of LIM and senescent cell antigen-like-containing domain protein 1
7lt9 B 255 B 272
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 255 and 272.
Details
Redox score ?
74
PDB code
7lt9
Structure name
crystal structure of ras suppressor-1 in complex with pinch-1 lim4-5 domains
Structure deposition date
2021-02-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
56
Minimum pKa ?
8
% buried
18
Peptide accession
P48059
Residue number A
255
Residue number B
272
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 255 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 272 of LIM and senescent cell antigen-like-containing domain protein 1
7d2u B 281 B 300
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 281 and 300.
Details
Redox score ?
73
PDB code
7d2u
Structure name
crystal structure of rsu1/pinch1_lim45c complex
Structure deposition date
2020-09-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
69
Minimum pKa ?
9
% buried
52
Peptide accession
P48059
Residue number A
281
Residue number B
300
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 281 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 300 of LIM and senescent cell antigen-like-containing domain protein 1
7lt9 B 278 B 300
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 278 and 300.
Details
Redox score ?
69
PDB code
7lt9
Structure name
crystal structure of ras suppressor-1 in complex with pinch-1 lim4-5 domains
Structure deposition date
2021-02-19
Thiol separation (Å)
3
Half-sphere exposure sum ?
59
Minimum pKa ?
13
% buried
nan
Peptide accession
P48059
Residue number A
278
Residue number B
300
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 278 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 300 of LIM and senescent cell antigen-like-containing domain protein 1
7d2u B 272 B 275
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 272 and 275.
Details
Redox score ?
69
PDB code
7d2u
Structure name
crystal structure of rsu1/pinch1_lim45c complex
Structure deposition date
2020-09-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
10
% buried
20
Peptide accession
P48059
Residue number A
272
Residue number B
275
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 272 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 275 of LIM and senescent cell antigen-like-containing domain protein 1
7d2u B 300 B 303
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 300 and 303.
Details
Redox score ?
68
PDB code
7d2u
Structure name
crystal structure of rsu1/pinch1_lim45c complex
Structure deposition date
2020-09-17
Thiol separation (Å)
3
Half-sphere exposure sum ?
58
Minimum pKa ?
13
% buried
54
Peptide accession
P48059
Residue number A
300
Residue number B
303
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 300 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 303 of LIM and senescent cell antigen-like-containing domain protein 1
4hi9 B 41 B 59
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 41 and 59.
Details
Redox score ?
66
PDB code
4hi9
Structure name
1
Structure deposition date
2012-10-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
68
Minimum pKa ?
11
% buried
65
Peptide accession
P48059
Residue number A
41
Residue number B
59
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 41 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 59 of LIM and senescent cell antigen-like-containing domain protein 1
3f6q B 10 B 35
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 10 and 35. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
3f6q
Structure name
crystal structure of integrin-linked kinase ankyrin repeat domain in complex with pinch1 lim1 domain
Structure deposition date
2008-11-06
Thiol separation (Å)
4
Half-sphere exposure sum ?
64
Minimum pKa ?
17
% buried
nan
Peptide accession
P48059
Residue number A
10
Residue number B
35
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 10 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 35 of LIM and senescent cell antigen-like-containing domain protein 1
7lt9 B 278 B 303
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 278 and 303. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
7lt9
Structure name
crystal structure of ras suppressor-1 in complex with pinch-1 lim4-5 domains
Structure deposition date
2021-02-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
19
% buried
nan
Peptide accession
P48059
Residue number A
278
Residue number B
303
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 278 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 303 of LIM and senescent cell antigen-like-containing domain protein 1
3f6q B 38 B 41
A redox-regulated disulphide may form within LIM and senescent cell antigen-like-containing domain protein 1 between cysteines 38 and 41. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
3f6q
Structure name
crystal structure of integrin-linked kinase ankyrin repeat domain in complex with pinch1 lim1 domain
Structure deposition date
2008-11-06
Thiol separation (Å)
4
Half-sphere exposure sum ?
70
Minimum pKa ?
20
% buried
nan
Peptide accession
P48059
Residue number A
38
Residue number B
41
Peptide name
LIM and senescent cell antigen-like-containing domain protein 1
Ligandability
Cysteine 38 of LIM and senescent cell antigen-like-containing domain protein 1
Cysteine 41 of LIM and senescent cell antigen-like-containing domain protein 1
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