Gap junction alpha-8 protein
Intramolecular
Cysteine 61 and cysteine 195
Cysteine 65 and cysteine 190
Cysteine 54 and cysteine 201
Cysteine 65 and cysteine 195
Cysteine 190 and cysteine 195
Cysteine 65 and cysteine 201
Cysteine 61 and cysteine 65
Cysteine 54 and cysteine 61
Cysteine 61 and cysteine 201
Cysteine 61 and cysteine 190
More...Cysteine 190 and cysteine 201
Cysteine 54 and cysteine 190
Cysteine 195 and cysteine 201
Cysteine 54 and cysteine 195
Cysteine 54 and cysteine 65
7jlw J 61 J 195
A redox-regulated disulphide may form within Gap junction alpha-8 protein between cysteines 61 and 195.
Details
Redox score ?
83
PDB code
7jlw
Structure name
sheep connexin-50 at 2
Structure deposition date
2020-07-30
Thiol separation (Å)
2
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55917
Residue number A
61
Residue number B
195
Peptide name
Gap junction alpha-8 protein
Ligandability
Cysteine 61 of Gap junction alpha-8 protein
Cysteine 195 of Gap junction alpha-8 protein
6mhy D 65 D 190
A redox-regulated disulphide may form within Gap junction alpha-8 protein between cysteines 65 and 190.
Details
Redox score ?
83
PDB code
6mhy
Structure name
structure of connexin-50 intercellular gap junction channel at 3
Structure deposition date
2018-09-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55917
Residue number A
65
Residue number B
190
Peptide name
Gap junction alpha-8 protein
Ligandability
Cysteine 65 of Gap junction alpha-8 protein
Cysteine 190 of Gap junction alpha-8 protein
7jmc K 54 K 201
A redox-regulated disulphide may form within Gap junction alpha-8 protein between cysteines 54 and 201.
Details
Redox score ?
81
PDB code
7jmc
Structure name
sheep connexin-50 at 2
Structure deposition date
2020-07-31
Thiol separation (Å)
2
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55917
Residue number A
54
Residue number B
201
Peptide name
Gap junction alpha-8 protein
Ligandability
Cysteine 54 of Gap junction alpha-8 protein
Cysteine 201 of Gap junction alpha-8 protein
7jjp L 65 L 195
A redox-regulated disulphide may form within Gap junction alpha-8 protein between cysteines 65 and 195.
Details
Redox score ?
77
PDB code
7jjp
Structure name
sheep connexin-50 at 1
Structure deposition date
2020-07-27
Thiol separation (Å)
3
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55917
Residue number A
65
Residue number B
195
Peptide name
Gap junction alpha-8 protein
Ligandability
Cysteine 65 of Gap junction alpha-8 protein
Cysteine 195 of Gap junction alpha-8 protein
7jm9 I 190 I 195
A redox-regulated disulphide may form within Gap junction alpha-8 protein between cysteines 190 and 195.
Details
Redox score ?
75
PDB code
7jm9
Structure name
sheep connexin-50 at 2
Structure deposition date
2020-07-31
Thiol separation (Å)
4
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55917
Residue number A
190
Residue number B
195
Peptide name
Gap junction alpha-8 protein
Ligandability
Cysteine 190 of Gap junction alpha-8 protein
Cysteine 195 of Gap junction alpha-8 protein
6mhy K 65 K 201
A redox-regulated disulphide may form within Gap junction alpha-8 protein between cysteines 65 and 201.
Details
Redox score ?
73
PDB code
6mhy
Structure name
structure of connexin-50 intercellular gap junction channel at 3
Structure deposition date
2018-09-18
Thiol separation (Å)
3
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55917
Residue number A
65
Residue number B
201
Peptide name
Gap junction alpha-8 protein
Ligandability
Cysteine 65 of Gap junction alpha-8 protein
Cysteine 201 of Gap junction alpha-8 protein
7jjp A 61 A 65
A redox-regulated disulphide may form within Gap junction alpha-8 protein between cysteines 61 and 65.
Details
Redox score ?
70
PDB code
7jjp
Structure name
sheep connexin-50 at 1
Structure deposition date
2020-07-27
Thiol separation (Å)
4
Half-sphere exposure sum ?
87
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55917
Residue number A
61
Residue number B
65
Peptide name
Gap junction alpha-8 protein
Ligandability
Cysteine 61 of Gap junction alpha-8 protein
Cysteine 65 of Gap junction alpha-8 protein
6mhy H 54 H 61
A redox-regulated disulphide may form within Gap junction alpha-8 protein between cysteines 54 and 61.
Details
Redox score ?
67
PDB code
6mhy
Structure name
structure of connexin-50 intercellular gap junction channel at 3
Structure deposition date
2018-09-18
Thiol separation (Å)
4
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55917
Residue number A
54
Residue number B
61
Peptide name
Gap junction alpha-8 protein
Ligandability
Cysteine 54 of Gap junction alpha-8 protein
Cysteine 61 of Gap junction alpha-8 protein
6mhy E 61 E 201
A redox-regulated disulphide may form within Gap junction alpha-8 protein between cysteines 61 and 201.
Details
Redox score ?
67
PDB code
6mhy
Structure name
structure of connexin-50 intercellular gap junction channel at 3
Structure deposition date
2018-09-18
Thiol separation (Å)
4
Half-sphere exposure sum ?
85
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55917
Residue number A
61
Residue number B
201
Peptide name
Gap junction alpha-8 protein
Ligandability
Cysteine 61 of Gap junction alpha-8 protein
Cysteine 201 of Gap junction alpha-8 protein
7jmc A 61 A 190
A redox-regulated disulphide may form within Gap junction alpha-8 protein between cysteines 61 and 190.
Details
Redox score ?
65
PDB code
7jmc
Structure name
sheep connexin-50 at 2
Structure deposition date
2020-07-31
Thiol separation (Å)
5
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55917
Residue number A
61
Residue number B
190
Peptide name
Gap junction alpha-8 protein
Ligandability
Cysteine 61 of Gap junction alpha-8 protein
Cysteine 190 of Gap junction alpha-8 protein
7jm9 L 190 L 201
A redox-regulated disulphide may form within Gap junction alpha-8 protein between cysteines 190 and 201.
Details
Redox score ?
65
PDB code
7jm9
Structure name
sheep connexin-50 at 2
Structure deposition date
2020-07-31
Thiol separation (Å)
5
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55917
Residue number A
190
Residue number B
201
Peptide name
Gap junction alpha-8 protein
Ligandability
Cysteine 190 of Gap junction alpha-8 protein
Cysteine 201 of Gap junction alpha-8 protein
7jm9 F 54 F 190
A redox-regulated disulphide may form within Gap junction alpha-8 protein between cysteines 54 and 190. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
7jm9
Structure name
sheep connexin-50 at 2
Structure deposition date
2020-07-31
Thiol separation (Å)
6
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55917
Residue number A
54
Residue number B
190
Peptide name
Gap junction alpha-8 protein
Ligandability
Cysteine 54 of Gap junction alpha-8 protein
Cysteine 190 of Gap junction alpha-8 protein
7jjp H 195 H 201
A redox-regulated disulphide may form within Gap junction alpha-8 protein between cysteines 195 and 201. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
7jjp
Structure name
sheep connexin-50 at 1
Structure deposition date
2020-07-27
Thiol separation (Å)
6
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55917
Residue number A
195
Residue number B
201
Peptide name
Gap junction alpha-8 protein
Ligandability
Cysteine 195 of Gap junction alpha-8 protein
Cysteine 201 of Gap junction alpha-8 protein
7jmc K 54 K 195
A redox-regulated disulphide may form within Gap junction alpha-8 protein between cysteines 54 and 195. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
58
PDB code
7jmc
Structure name
sheep connexin-50 at 2
Structure deposition date
2020-07-31
Thiol separation (Å)
6
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55917
Residue number A
54
Residue number B
195
Peptide name
Gap junction alpha-8 protein
Ligandability
Cysteine 54 of Gap junction alpha-8 protein
Cysteine 195 of Gap junction alpha-8 protein
7jlw E 54 E 65
A redox-regulated disulphide may form within Gap junction alpha-8 protein between cysteines 54 and 65. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
7jlw
Structure name
sheep connexin-50 at 2
Structure deposition date
2020-07-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
84
Minimum pKa ?
17
% buried
nan
Peptide accession
P55917
Residue number A
54
Residue number B
65
Peptide name
Gap junction alpha-8 protein
Ligandability
Cysteine 54 of Gap junction alpha-8 protein
Cysteine 65 of Gap junction alpha-8 protein
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