CX3C chemokine receptor 1
Intramolecular
Cysteine 102 and cysteine 175
Cysteine 8 and cysteine 221
Cysteine 221 and cysteine 210
Cysteine 286 and cysteine 287
Cysteine 8 and cysteine 210
Cysteine 221 and cysteine 278
Cysteine 175 and cysteine 278
Cysteine 102 and cysteine 278
Cysteine 210 and cysteine 175
Cysteine 210 and cysteine 278
More...Cysteine 221 and cysteine 265
Cysteine 12 and cysteine 265
Cysteine 12 and cysteine 221
7xbw R 102 R 175
A redox-regulated disulphide may form within CX3C chemokine receptor 1 between cysteines 102 and 175.
Details
Redox score ?
86
PDB code
7xbw
Structure name
cryo-em structure of the human chemokine receptor cx3cr1 in complex with gi1
Structure deposition date
2022-03-22
Thiol separation (Å)
2
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49238
Residue number A
102
Residue number B
175
Peptide name
CX3C chemokine receptor 1
Ligandability
Cysteine 102 of CX3C chemokine receptor 1
Cysteine 175 of CX3C chemokine receptor 1
7xbx R 8 R 34
A redox-regulated disulphide may form within CX3C chemokine receptor 1 between cysteines 8 and 221 (8 and 34 respectively in this structure).
Details
Redox score ?
83
PDB code
7xbx
Structure name
cryo-em structure of the human chemokine receptor cx3cr1 in complex with cx3cl1 and gi1
Structure deposition date
2022-03-22
Thiol separation (Å)
2
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49238
Residue number A
8
Residue number B
221
Peptide name
CX3C chemokine receptor 1
Ligandability
Cysteine 8 of CX3C chemokine receptor 1
Cysteine 221 of CX3C chemokine receptor 1
Cysteine 8 in protein A could not be asigned to a Uniprot residue.
7xbx R 34 R 35
A redox-regulated disulphide may form within CX3C chemokine receptor 1 between cysteines 221 and 210 (34 and 35 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
51
PDB code
7xbx
Structure name
cryo-em structure of the human chemokine receptor cx3cr1 in complex with cx3cl1 and gi1
Structure deposition date
2022-03-22
Thiol separation (Å)
7
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49238
Residue number A
221
Residue number B
210
Peptide name
CX3C chemokine receptor 1
Ligandability
Cysteine 221 of CX3C chemokine receptor 1
Cysteine 210 of CX3C chemokine receptor 1
7xbw R 286 R 287
A redox-regulated disulphide may form within CX3C chemokine receptor 1 between cysteines 286 and 287. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
7xbw
Structure name
cryo-em structure of the human chemokine receptor cx3cr1 in complex with gi1
Structure deposition date
2022-03-22
Thiol separation (Å)
7
Half-sphere exposure sum ?
84
Minimum pKa ?
11
% buried
78
Peptide accession
P49238
Residue number A
286
Residue number B
287
Peptide name
CX3C chemokine receptor 1
Ligandability
Cysteine 286 of CX3C chemokine receptor 1
Cysteine 287 of CX3C chemokine receptor 1
7xbx R 8 R 35
A redox-regulated disulphide may form within CX3C chemokine receptor 1 between cysteines 8 and 210 (8 and 35 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
7xbx
Structure name
cryo-em structure of the human chemokine receptor cx3cr1 in complex with cx3cl1 and gi1
Structure deposition date
2022-03-22
Thiol separation (Å)
9
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49238
Residue number A
8
Residue number B
210
Peptide name
CX3C chemokine receptor 1
Ligandability
Cysteine 8 of CX3C chemokine receptor 1
Cysteine 210 of CX3C chemokine receptor 1
Cysteine 8 in protein A could not be asigned to a Uniprot residue.
7xbx R 34 R 278
A redox-regulated disulphide may form within CX3C chemokine receptor 1 between cysteines 221 and 278 (34 and 278 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
7xbx
Structure name
cryo-em structure of the human chemokine receptor cx3cr1 in complex with cx3cl1 and gi1
Structure deposition date
2022-03-22
Thiol separation (Å)
9
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49238
Residue number A
221
Residue number B
278
Peptide name
CX3C chemokine receptor 1
Ligandability
Cysteine 221 of CX3C chemokine receptor 1
Cysteine 278 of CX3C chemokine receptor 1
Cysteine 278 in protein B could not be asigned to a Uniprot residue.
7xbx R 277 R 278
A redox-regulated disulphide may form within CX3C chemokine receptor 1 between cysteines 175 and 278 (277 and 278 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
7xbx
Structure name
cryo-em structure of the human chemokine receptor cx3cr1 in complex with cx3cl1 and gi1
Structure deposition date
2022-03-22
Thiol separation (Å)
9
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49238
Residue number A
175
Residue number B
278
Peptide name
CX3C chemokine receptor 1
Ligandability
Cysteine 175 of CX3C chemokine receptor 1
Cysteine 278 of CX3C chemokine receptor 1
Cysteine 278 in protein B could not be asigned to a Uniprot residue.
7xbx R 204 R 278
A redox-regulated disulphide may form within CX3C chemokine receptor 1 between cysteines 102 and 278 (204 and 278 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
7xbx
Structure name
cryo-em structure of the human chemokine receptor cx3cr1 in complex with cx3cl1 and gi1
Structure deposition date
2022-03-22
Thiol separation (Å)
10
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49238
Residue number A
102
Residue number B
278
Peptide name
CX3C chemokine receptor 1
Ligandability
Cysteine 102 of CX3C chemokine receptor 1
Cysteine 278 of CX3C chemokine receptor 1
Cysteine 278 in protein B could not be asigned to a Uniprot residue.
7xbx R 35 R 277
A redox-regulated disulphide may form within CX3C chemokine receptor 1 between cysteines 210 and 175 (35 and 277 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
35
PDB code
7xbx
Structure name
cryo-em structure of the human chemokine receptor cx3cr1 in complex with cx3cl1 and gi1
Structure deposition date
2022-03-22
Thiol separation (Å)
10
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49238
Residue number A
210
Residue number B
175
Peptide name
CX3C chemokine receptor 1
Ligandability
Cysteine 210 of CX3C chemokine receptor 1
Cysteine 175 of CX3C chemokine receptor 1
7xbx R 35 R 278
A redox-regulated disulphide may form within CX3C chemokine receptor 1 between cysteines 210 and 278 (35 and 278 respectively in this structure).
Details
Redox score ?
nan
PDB code
7xbx
Structure name
cryo-em structure of the human chemokine receptor cx3cr1 in complex with cx3cl1 and gi1
Structure deposition date
2022-03-22
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49238
Residue number A
210
Residue number B
278
Peptide name
CX3C chemokine receptor 1
Ligandability
Cysteine 210 of CX3C chemokine receptor 1
Cysteine 278 of CX3C chemokine receptor 1
Cysteine 278 in protein B could not be asigned to a Uniprot residue.
7xbx R 50 R 367
A redox-regulated disulphide may form within CX3C chemokine receptor 1 between cysteines 221 and 265 (50 and 367 respectively in this structure).
Details
Redox score ?
nan
PDB code
7xbx
Structure name
cryo-em structure of the human chemokine receptor cx3cr1 in complex with cx3cl1 and gi1
Structure deposition date
2022-03-22
Thiol separation (Å)
8
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
nan
Peptide accession
P49238
Residue number A
221
Residue number B
265
Peptide name
CX3C chemokine receptor 1
Ligandability
Cysteine 221 of CX3C chemokine receptor 1
Cysteine 265 of CX3C chemokine receptor 1
Uncertain whether structure cysteine 50 has been assigned to correct residue.
7xbx R 12 R 367
A redox-regulated disulphide may form within CX3C chemokine receptor 1 between cysteines 12 and 265 (12 and 367 respectively in this structure).
Details
Redox score ?
nan
PDB code
7xbx
Structure name
cryo-em structure of the human chemokine receptor cx3cr1 in complex with cx3cl1 and gi1
Structure deposition date
2022-03-22
Thiol separation (Å)
8
Half-sphere exposure sum ?
59
Minimum pKa ?
9
% buried
nan
Peptide accession
P49238
Residue number A
12
Residue number B
265
Peptide name
CX3C chemokine receptor 1
Ligandability
Cysteine 12 of CX3C chemokine receptor 1
Cysteine 265 of CX3C chemokine receptor 1
Cysteine 12 in protein A could not be asigned to a Uniprot residue.
7xbx R 12 R 50
A redox-regulated disulphide may form within CX3C chemokine receptor 1 between cysteines 12 and 221 (12 and 50 respectively in this structure).
Details
Redox score ?
nan
PDB code
7xbx
Structure name
cryo-em structure of the human chemokine receptor cx3cr1 in complex with cx3cl1 and gi1
Structure deposition date
2022-03-22
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49238
Residue number A
12
Residue number B
221
Peptide name
CX3C chemokine receptor 1
Ligandability
Cysteine 12 of CX3C chemokine receptor 1
Cysteine 221 of CX3C chemokine receptor 1
Cysteine 12 in protein A could not be asigned to a Uniprot residue.
Uncertain whether structure cysteine 50 has been assigned to correct residue.
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