ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

39S ribosomal protein L19, mitochondrial

Intramolecular
Cysteine 137 and cysteine 163 L
A redox-regulated disulphide may form within 39S ribosomal protein L19, mitochondrial between cysteines 137 and 163. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
27
PDB code
7oie
Structure name
cryo-em structure of late human 39s mitoribosome assembly intermediates, state 5b
Structure deposition date
2021-05-11
Thiol separation (Å)
10
Half-sphere exposure sum ?
82
Minimum pKa ?
12
% buried
100
Peptide accession
P49406
Residue number A
137
Residue number B
163
Peptide name
39S ribosomal protein L19, mitochondrial

Ligandability

Cysteine 137 of 39S ribosomal protein L19, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 163 of 39S ribosomal protein L19, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: