Ubiquitin-conjugating enzyme E2 R1

Intermolecular

A redox-regulated disulphide may form between two units of Ubiquitin-conjugating enzyme E2 R1 at cysteines 93 and 93. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

3rz3

Structure name

human cdc34 e2 in complex with cc0651 inhibitor

Structure deposition date

2011-05-11

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide A name

Ubiquitin-conjugating enzyme E2 R1

Peptide B name

Ubiquitin-conjugating enzyme E2 R1

Peptide A accession

P49427

Peptide B accession

P49427

Peptide A residue number

Peptide B residue number

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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