ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Inositol polyphosphate 1-phosphatase

Intramolecular
Cysteine 181 and cysteine 297
A redox-regulated disulphide may form within Inositol polyphosphate 1-phosphatase between cysteines 181 and 297. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
44
PDB code
6wrr
Structure name
crystal structure of inositol polyphosphate 1-phosphatase inpp1 in complex gadolinium and lithium at 2
Structure deposition date
2020-04-30
Thiol separation (Å)
8
Half-sphere exposure sum ?
88
Minimum pKa ?
nan
% buried
nan
Peptide accession
P21327
Residue number A
181
Residue number B
297
Peptide name
Inositol polyphosphate 1-phosphatase

Ligandability

Cysteine 181 of Inositol polyphosphate 1-phosphatase

Cysteine 297 of Inositol polyphosphate 1-phosphatase

If this tool was useful for finding a disulphide, please cite: