ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Choline-phosphate cytidylyltransferase A

Intermolecular
Cysteine 139 and cysteine 139
A redox-regulated disulphide may form between two units of Choline-phosphate cytidylyltransferase A at cysteines 139 and 139. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
27
PDB code
3hl4
Structure name
crystal structure of a mammalian ctp:phosphocholine cytidylyltransferase with cdp-choline
Structure deposition date
2009-05-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
107
Minimum pKa ?
11
% buried
100
Peptide A name
Choline-phosphate cytidylyltransferase A
Peptide B name
Choline-phosphate cytidylyltransferase A
Peptide A accession
P19836
Peptide B accession
P19836
Peptide A residue number
139
Peptide B residue number
139

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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