Placenta growth factor
Intermolecular
Cysteine 86 and cysteine 77
Cysteine 87 and cysteine 77
Cysteine 130 and cysteine 77
Cysteine 77 and cysteine 94
Cysteine 77 and cysteine 52
Intramolecular
Cysteine 83 and cysteine 128
Cysteine 87 and cysteine 130
Cysteine 52 and cysteine 94
Cysteine 52 and cysteine 130
Cysteine 94 and cysteine 128
More...Cysteine 83 and cysteine 94
Cysteine 52 and cysteine 128
Cysteine 94 and cysteine 130
Cysteine 87 and cysteine 94
Cysteine 52 and cysteine 87
Cysteine 52 and cysteine 83
Cysteine 86 and cysteine 87
Cysteine 128 and cysteine 130
Cysteine 86 and cysteine 130
Cysteine 86 and cysteine 94
Cysteine 83 and cysteine 130
Cysteine 87 and cysteine 128
Cysteine 83 and cysteine 87
Cysteine 52 and cysteine 86
1fzv A 69 B 60
A redox-regulated disulphide may form between two units of Placenta growth factor at cysteines 86 and 77 (69 and 60 respectively in this structure).
Details
Redox score ?
80
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
2
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide A name
Placenta growth factor
Peptide B name
Placenta growth factor
Peptide A accession
P49763
Peptide B accession
P49763
Peptide A residue number
86
Peptide B residue number
77
Ligandability
Cysteine 86 of Placenta growth factor
Cysteine 77 of Placenta growth factor
1fzv A 70 B 60
A redox-regulated disulphide may form between two units of Placenta growth factor at cysteines 87 and 77 (70 and 60 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
8
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide A name
Placenta growth factor
Peptide B name
Placenta growth factor
Peptide A accession
P49763
Peptide B accession
P49763
Peptide A residue number
87
Peptide B residue number
77
Ligandability
Cysteine 87 of Placenta growth factor
Cysteine 77 of Placenta growth factor
1fzv A 113 B 60
A redox-regulated disulphide may form between two units of Placenta growth factor at cysteines 130 and 77 (113 and 60 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide A name
Placenta growth factor
Peptide B name
Placenta growth factor
Peptide A accession
P49763
Peptide B accession
P49763
Peptide A residue number
130
Peptide B residue number
77
Ligandability
Cysteine 130 of Placenta growth factor
Cysteine 77 of Placenta growth factor
1rv6 V 59 W 76
A redox-regulated disulphide may form between two units of Placenta growth factor at cysteines 77 and 94 (59 and 76 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
1rv6
Structure name
crystal structure of plgf in complex with domain 2 of vegfr1
Structure deposition date
2003-12-12
Thiol separation (Å)
10
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide A name
Placenta growth factor
Peptide B name
Placenta growth factor
Peptide A accession
P49763
Peptide B accession
P49763
Peptide A residue number
77
Peptide B residue number
94
Ligandability
Cysteine 77 of Placenta growth factor
Cysteine 94 of Placenta growth factor
1fzv A 60 B 35
A redox-regulated disulphide may form between two units of Placenta growth factor at cysteines 77 and 52 (60 and 35 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
10
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide A name
Placenta growth factor
Peptide B name
Placenta growth factor
Peptide A accession
P49763
Peptide B accession
P49763
Peptide A residue number
77
Peptide B residue number
52
Ligandability
Cysteine 77 of Placenta growth factor
Cysteine 52 of Placenta growth factor
1fzv B 66 B 111
A redox-regulated disulphide may form within Placenta growth factor between cysteines 83 and 128 (66 and 111 respectively in this structure).
Details
Redox score ?
88
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
2
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
83
Residue number B
128
Peptide name
Placenta growth factor
Ligandability
Cysteine 83 of Placenta growth factor
Cysteine 128 of Placenta growth factor
1fzv A 70 A 113
A redox-regulated disulphide may form within Placenta growth factor between cysteines 87 and 130 (70 and 113 respectively in this structure).
Details
Redox score ?
85
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
87
Residue number B
130
Peptide name
Placenta growth factor
Ligandability
Cysteine 87 of Placenta growth factor
Cysteine 130 of Placenta growth factor
1fzv A 35 A 77
A redox-regulated disulphide may form within Placenta growth factor between cysteines 52 and 94 (35 and 77 respectively in this structure).
Details
Redox score ?
84
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
2
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
52
Residue number B
94
Peptide name
Placenta growth factor
Ligandability
Cysteine 52 of Placenta growth factor
Cysteine 94 of Placenta growth factor
1fzv B 35 B 113
A redox-regulated disulphide may form within Placenta growth factor between cysteines 52 and 130 (35 and 113 respectively in this structure).
Details
Redox score ?
73
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
52
Residue number B
130
Peptide name
Placenta growth factor
Ligandability
Cysteine 52 of Placenta growth factor
Cysteine 130 of Placenta growth factor
1fzv A 77 A 111
A redox-regulated disulphide may form within Placenta growth factor between cysteines 94 and 128 (77 and 111 respectively in this structure).
Details
Redox score ?
72
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
5
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
94
Residue number B
128
Peptide name
Placenta growth factor
Ligandability
Cysteine 94 of Placenta growth factor
Cysteine 128 of Placenta growth factor
1fzv B 66 B 77
A redox-regulated disulphide may form within Placenta growth factor between cysteines 83 and 94 (66 and 77 respectively in this structure).
Details
Redox score ?
69
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
5
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
83
Residue number B
94
Peptide name
Placenta growth factor
Ligandability
Cysteine 83 of Placenta growth factor
Cysteine 94 of Placenta growth factor
1rv6 V 34 V 110
A redox-regulated disulphide may form within Placenta growth factor between cysteines 52 and 128 (34 and 110 respectively in this structure).
Details
Redox score ?
67
PDB code
1rv6
Structure name
crystal structure of plgf in complex with domain 2 of vegfr1
Structure deposition date
2003-12-12
Thiol separation (Å)
5
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
52
Residue number B
128
Peptide name
Placenta growth factor
Ligandability
Cysteine 52 of Placenta growth factor
Cysteine 128 of Placenta growth factor
1fzv B 77 B 113
A redox-regulated disulphide may form within Placenta growth factor between cysteines 94 and 130 (77 and 113 respectively in this structure).
Details
Redox score ?
67
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
5
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
94
Residue number B
130
Peptide name
Placenta growth factor
Ligandability
Cysteine 94 of Placenta growth factor
Cysteine 130 of Placenta growth factor
1rv6 V 69 V 76
A redox-regulated disulphide may form within Placenta growth factor between cysteines 87 and 94 (69 and 76 respectively in this structure).
Details
Redox score ?
66
PDB code
1rv6
Structure name
crystal structure of plgf in complex with domain 2 of vegfr1
Structure deposition date
2003-12-12
Thiol separation (Å)
5
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
87
Residue number B
94
Peptide name
Placenta growth factor
Ligandability
Cysteine 87 of Placenta growth factor
Cysteine 94 of Placenta growth factor
1rv6 W 34 W 69
A redox-regulated disulphide may form within Placenta growth factor between cysteines 52 and 87 (34 and 69 respectively in this structure).
Details
Redox score ?
66
PDB code
1rv6
Structure name
crystal structure of plgf in complex with domain 2 of vegfr1
Structure deposition date
2003-12-12
Thiol separation (Å)
4
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
52
Residue number B
87
Peptide name
Placenta growth factor
Ligandability
Cysteine 52 of Placenta growth factor
Cysteine 87 of Placenta growth factor
1fzv A 35 A 66
A redox-regulated disulphide may form within Placenta growth factor between cysteines 52 and 83 (35 and 66 respectively in this structure).
Details
Redox score ?
63
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
6
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
52
Residue number B
83
Peptide name
Placenta growth factor
Ligandability
Cysteine 52 of Placenta growth factor
Cysteine 83 of Placenta growth factor
1fzv A 69 A 70
A redox-regulated disulphide may form within Placenta growth factor between cysteines 86 and 87 (69 and 70 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
51
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
7
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
86
Residue number B
87
Peptide name
Placenta growth factor
Ligandability
Cysteine 86 of Placenta growth factor
Cysteine 87 of Placenta growth factor
1rv6 V 110 V 112
A redox-regulated disulphide may form within Placenta growth factor between cysteines 128 and 130 (110 and 112 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
1rv6
Structure name
crystal structure of plgf in complex with domain 2 of vegfr1
Structure deposition date
2003-12-12
Thiol separation (Å)
9
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
128
Residue number B
130
Peptide name
Placenta growth factor
Ligandability
Cysteine 128 of Placenta growth factor
Cysteine 130 of Placenta growth factor
1fzv A 69 A 113
A redox-regulated disulphide may form within Placenta growth factor between cysteines 86 and 130 (69 and 113 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
8
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
86
Residue number B
130
Peptide name
Placenta growth factor
Ligandability
Cysteine 86 of Placenta growth factor
Cysteine 130 of Placenta growth factor
1fzv B 69 B 77
A redox-regulated disulphide may form within Placenta growth factor between cysteines 86 and 94 (69 and 77 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
86
Residue number B
94
Peptide name
Placenta growth factor
Ligandability
Cysteine 86 of Placenta growth factor
Cysteine 94 of Placenta growth factor
1fzv B 66 B 113
A redox-regulated disulphide may form within Placenta growth factor between cysteines 83 and 130 (66 and 113 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
83
Residue number B
130
Peptide name
Placenta growth factor
Ligandability
Cysteine 83 of Placenta growth factor
Cysteine 130 of Placenta growth factor
1fzv A 70 A 111
A redox-regulated disulphide may form within Placenta growth factor between cysteines 87 and 128 (70 and 111 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
1fzv
Structure name
the crystal structure of human placenta growth factor-1 (plgf-1), an angiogenic protein at 2
Structure deposition date
2000-10-04
Thiol separation (Å)
10
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
87
Residue number B
128
Peptide name
Placenta growth factor
Ligandability
Cysteine 87 of Placenta growth factor
Cysteine 128 of Placenta growth factor
1rv6 W 65 W 69
A redox-regulated disulphide may form within Placenta growth factor between cysteines 83 and 87 (65 and 69 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
1rv6
Structure name
crystal structure of plgf in complex with domain 2 of vegfr1
Structure deposition date
2003-12-12
Thiol separation (Å)
9
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
83
Residue number B
87
Peptide name
Placenta growth factor
Ligandability
Cysteine 83 of Placenta growth factor
Cysteine 87 of Placenta growth factor
1rv6 V 34 V 68
A redox-regulated disulphide may form within Placenta growth factor between cysteines 52 and 86 (34 and 68 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
35
PDB code
1rv6
Structure name
crystal structure of plgf in complex with domain 2 of vegfr1
Structure deposition date
2003-12-12
Thiol separation (Å)
10
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49763
Residue number A
52
Residue number B
86
Peptide name
Placenta growth factor
Ligandability
Cysteine 52 of Placenta growth factor
Cysteine 86 of Placenta growth factor
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