Vascular endothelial growth factor B
Intermolecular
Cysteine 72 and cysteine 81
Cysteine 72 and cysteine 89
Cysteine 72 and cysteine 82
Cysteine 72 and cysteine 124
Cysteine 47 and cysteine 72
Intramolecular
Cysteine 78 and cysteine 122
Cysteine 82 and cysteine 124
Cysteine 47 and cysteine 89
Cysteine 47 and cysteine 124
Cysteine 89 and cysteine 122
More...Cysteine 47 and cysteine 122
Cysteine 89 and cysteine 124
Cysteine 78 and cysteine 89
Cysteine 47 and cysteine 82
Cysteine 82 and cysteine 89
Cysteine 47 and cysteine 78
Cysteine 81 and cysteine 82
Cysteine 122 and cysteine 124
Cysteine 81 and cysteine 89
Cysteine 81 and cysteine 124
Cysteine 82 and cysteine 122
Cysteine 47 and cysteine 81
Cysteine 78 and cysteine 82
Cysteine 78 and cysteine 124
2vwe A 51 B 60
A redox-regulated disulphide may form between two units of Vascular endothelial growth factor B at cysteines 72 and 81 (51 and 60 respectively in this structure).
Details
Redox score ?
79
PDB code
2vwe
Structure name
crystal structure of vascular endothelial growth factor-b in complex with a neutralizing antibody fab fragment
Structure deposition date
2008-06-23
Thiol separation (Å)
2
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide A name
Vascular endothelial growth factor B
Peptide B name
Vascular endothelial growth factor B
Peptide A accession
P49765
Peptide B accession
P49765
Peptide A residue number
72
Peptide B residue number
81
Ligandability
Cysteine 72 of Vascular endothelial growth factor B
Cysteine 81 of Vascular endothelial growth factor B
2c7w A 51 B 68
A redox-regulated disulphide may form between two units of Vascular endothelial growth factor B at cysteines 72 and 89 (51 and 68 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
2c7w
Structure name
crystal structure of human vascular endothelial growth factor-b: identification of amino acids important for angiogeninc activity
Structure deposition date
2005-11-29
Thiol separation (Å)
9
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide A name
Vascular endothelial growth factor B
Peptide B name
Vascular endothelial growth factor B
Peptide A accession
P49765
Peptide B accession
P49765
Peptide A residue number
72
Peptide B residue number
89
Ligandability
Cysteine 72 of Vascular endothelial growth factor B
Cysteine 89 of Vascular endothelial growth factor B
2vwe A 51 B 61
A redox-regulated disulphide may form between two units of Vascular endothelial growth factor B at cysteines 72 and 82 (51 and 61 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
2vwe
Structure name
crystal structure of vascular endothelial growth factor-b in complex with a neutralizing antibody fab fragment
Structure deposition date
2008-06-23
Thiol separation (Å)
9
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide A name
Vascular endothelial growth factor B
Peptide B name
Vascular endothelial growth factor B
Peptide A accession
P49765
Peptide B accession
P49765
Peptide A residue number
72
Peptide B residue number
82
Ligandability
Cysteine 72 of Vascular endothelial growth factor B
Cysteine 82 of Vascular endothelial growth factor B
2c7w A 51 B 103
A redox-regulated disulphide may form between two units of Vascular endothelial growth factor B at cysteines 72 and 124 (51 and 103 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
2c7w
Structure name
crystal structure of human vascular endothelial growth factor-b: identification of amino acids important for angiogeninc activity
Structure deposition date
2005-11-29
Thiol separation (Å)
9
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide A name
Vascular endothelial growth factor B
Peptide B name
Vascular endothelial growth factor B
Peptide A accession
P49765
Peptide B accession
P49765
Peptide A residue number
72
Peptide B residue number
124
Ligandability
Cysteine 72 of Vascular endothelial growth factor B
Cysteine 124 of Vascular endothelial growth factor B
2xac A 26 B 51
A redox-regulated disulphide may form between two units of Vascular endothelial growth factor B at cysteines 47 and 72 (26 and 51 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
2xac
Structure name
structural insights into the binding of vegf-b by vegfr-1d2: recognition and specificity
Structure deposition date
2010-03-30
Thiol separation (Å)
9
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide A name
Vascular endothelial growth factor B
Peptide B name
Vascular endothelial growth factor B
Peptide A accession
P49765
Peptide B accession
P49765
Peptide A residue number
47
Peptide B residue number
72
Ligandability
Cysteine 47 of Vascular endothelial growth factor B
Cysteine 72 of Vascular endothelial growth factor B
2xac A 57 A 101
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 78 and 122 (57 and 101 respectively in this structure).
Details
Redox score ?
86
PDB code
2xac
Structure name
structural insights into the binding of vegf-b by vegfr-1d2: recognition and specificity
Structure deposition date
2010-03-30
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
78
Residue number B
122
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 78 of Vascular endothelial growth factor B
Cysteine 122 of Vascular endothelial growth factor B
2vwe A 61 A 103
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 82 and 124 (61 and 103 respectively in this structure).
Details
Redox score ?
83
PDB code
2vwe
Structure name
crystal structure of vascular endothelial growth factor-b in complex with a neutralizing antibody fab fragment
Structure deposition date
2008-06-23
Thiol separation (Å)
2
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
82
Residue number B
124
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 82 of Vascular endothelial growth factor B
Cysteine 124 of Vascular endothelial growth factor B
2xac B 26 B 68
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 47 and 89 (26 and 68 respectively in this structure).
Details
Redox score ?
82
PDB code
2xac
Structure name
structural insights into the binding of vegf-b by vegfr-1d2: recognition and specificity
Structure deposition date
2010-03-30
Thiol separation (Å)
2
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
47
Residue number B
89
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 47 of Vascular endothelial growth factor B
Cysteine 89 of Vascular endothelial growth factor B
2c7w B 26 B 103
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 47 and 124 (26 and 103 respectively in this structure).
Details
Redox score ?
74
PDB code
2c7w
Structure name
crystal structure of human vascular endothelial growth factor-b: identification of amino acids important for angiogeninc activity
Structure deposition date
2005-11-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
47
Residue number B
124
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 47 of Vascular endothelial growth factor B
Cysteine 124 of Vascular endothelial growth factor B
2c7w B 68 B 101
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 89 and 122 (68 and 101 respectively in this structure).
Details
Redox score ?
72
PDB code
2c7w
Structure name
crystal structure of human vascular endothelial growth factor-b: identification of amino acids important for angiogeninc activity
Structure deposition date
2005-11-29
Thiol separation (Å)
5
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
89
Residue number B
122
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 89 of Vascular endothelial growth factor B
Cysteine 122 of Vascular endothelial growth factor B
2c7w A 26 A 101
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 47 and 122 (26 and 101 respectively in this structure).
Details
Redox score ?
69
PDB code
2c7w
Structure name
crystal structure of human vascular endothelial growth factor-b: identification of amino acids important for angiogeninc activity
Structure deposition date
2005-11-29
Thiol separation (Å)
5
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
47
Residue number B
122
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 47 of Vascular endothelial growth factor B
Cysteine 122 of Vascular endothelial growth factor B
2xac A 68 A 103
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 89 and 124 (68 and 103 respectively in this structure).
Details
Redox score ?
69
PDB code
2xac
Structure name
structural insights into the binding of vegf-b by vegfr-1d2: recognition and specificity
Structure deposition date
2010-03-30
Thiol separation (Å)
5
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
89
Residue number B
124
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 89 of Vascular endothelial growth factor B
Cysteine 124 of Vascular endothelial growth factor B
2c7w A 57 A 68
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 78 and 89 (57 and 68 respectively in this structure).
Details
Redox score ?
69
PDB code
2c7w
Structure name
crystal structure of human vascular endothelial growth factor-b: identification of amino acids important for angiogeninc activity
Structure deposition date
2005-11-29
Thiol separation (Å)
5
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
78
Residue number B
89
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 78 of Vascular endothelial growth factor B
Cysteine 89 of Vascular endothelial growth factor B
2c7w B 26 B 61
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 47 and 82 (26 and 61 respectively in this structure).
Details
Redox score ?
69
PDB code
2c7w
Structure name
crystal structure of human vascular endothelial growth factor-b: identification of amino acids important for angiogeninc activity
Structure deposition date
2005-11-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
47
Residue number B
82
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 47 of Vascular endothelial growth factor B
Cysteine 82 of Vascular endothelial growth factor B
2xac B 61 B 68
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 82 and 89 (61 and 68 respectively in this structure).
Details
Redox score ?
66
PDB code
2xac
Structure name
structural insights into the binding of vegf-b by vegfr-1d2: recognition and specificity
Structure deposition date
2010-03-30
Thiol separation (Å)
5
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
82
Residue number B
89
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 82 of Vascular endothelial growth factor B
Cysteine 89 of Vascular endothelial growth factor B
2xac B 26 B 57
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 47 and 78 (26 and 57 respectively in this structure).
Details
Redox score ?
62
PDB code
2xac
Structure name
structural insights into the binding of vegf-b by vegfr-1d2: recognition and specificity
Structure deposition date
2010-03-30
Thiol separation (Å)
5
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
47
Residue number B
78
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 47 of Vascular endothelial growth factor B
Cysteine 78 of Vascular endothelial growth factor B
2c7w A 60 A 61
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 81 and 82 (60 and 61 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
51
PDB code
2c7w
Structure name
crystal structure of human vascular endothelial growth factor-b: identification of amino acids important for angiogeninc activity
Structure deposition date
2005-11-29
Thiol separation (Å)
7
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
81
Residue number B
82
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 81 of Vascular endothelial growth factor B
Cysteine 82 of Vascular endothelial growth factor B
2vwe B 101 B 103
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 122 and 124 (101 and 103 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
2vwe
Structure name
crystal structure of vascular endothelial growth factor-b in complex with a neutralizing antibody fab fragment
Structure deposition date
2008-06-23
Thiol separation (Å)
9
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
122
Residue number B
124
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 122 of Vascular endothelial growth factor B
Cysteine 124 of Vascular endothelial growth factor B
2xac B 60 B 68
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 81 and 89 (60 and 68 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
2xac
Structure name
structural insights into the binding of vegf-b by vegfr-1d2: recognition and specificity
Structure deposition date
2010-03-30
Thiol separation (Å)
9
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
81
Residue number B
89
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 81 of Vascular endothelial growth factor B
Cysteine 89 of Vascular endothelial growth factor B
2vwe A 60 A 103
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 81 and 124 (60 and 103 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
2vwe
Structure name
crystal structure of vascular endothelial growth factor-b in complex with a neutralizing antibody fab fragment
Structure deposition date
2008-06-23
Thiol separation (Å)
9
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
81
Residue number B
124
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 81 of Vascular endothelial growth factor B
Cysteine 124 of Vascular endothelial growth factor B
2vwe A 61 A 101
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 82 and 122 (61 and 101 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
2vwe
Structure name
crystal structure of vascular endothelial growth factor-b in complex with a neutralizing antibody fab fragment
Structure deposition date
2008-06-23
Thiol separation (Å)
9
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
82
Residue number B
122
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 82 of Vascular endothelial growth factor B
Cysteine 122 of Vascular endothelial growth factor B
2vwe A 26 A 60
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 47 and 81 (26 and 60 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
2vwe
Structure name
crystal structure of vascular endothelial growth factor-b in complex with a neutralizing antibody fab fragment
Structure deposition date
2008-06-23
Thiol separation (Å)
9
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
47
Residue number B
81
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 47 of Vascular endothelial growth factor B
Cysteine 81 of Vascular endothelial growth factor B
2c7w B 57 B 61
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 78 and 82 (57 and 61 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
2c7w
Structure name
crystal structure of human vascular endothelial growth factor-b: identification of amino acids important for angiogeninc activity
Structure deposition date
2005-11-29
Thiol separation (Å)
9
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
78
Residue number B
82
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 78 of Vascular endothelial growth factor B
Cysteine 82 of Vascular endothelial growth factor B
2vwe B 57 B 103
A redox-regulated disulphide may form within Vascular endothelial growth factor B between cysteines 78 and 124 (57 and 103 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
2vwe
Structure name
crystal structure of vascular endothelial growth factor-b in complex with a neutralizing antibody fab fragment
Structure deposition date
2008-06-23
Thiol separation (Å)
10
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
P49765
Residue number A
78
Residue number B
124
Peptide name
Vascular endothelial growth factor B
Ligandability
Cysteine 78 of Vascular endothelial growth factor B
Cysteine 124 of Vascular endothelial growth factor B
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