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E3 SUMO-protein ligase RanBP2

Intermolecular
Cysteine 3071 and cysteine 3213
Intramolecular
Cysteine 1549 and cysteine 1563
Cysteine 1787 and cysteine 1801
Cysteine 1485 and cysteine 1499 L
Cysteine 1421 and cysteine 1435 L
Cysteine 1790 and cysteine 1801
Cysteine 1552 and cysteine 1563
Cysteine 1424 and cysteine 1435
Cysteine 1563 and cysteine 1566
Cysteine 1488 and cysteine 1499 L
More...
Cysteine 1801 and cysteine 1804
Cysteine 1435 and cysteine 1438
Cysteine 1612 and cysteine 1744
Cysteine 1499 and cysteine 1502 L
Cysteine 1612 and cysteine 1626
Cysteine 1615 and cysteine 1744
Cysteine 1744 and cysteine 1747
Cysteine 1615 and cysteine 1626
Cysteine 1626 and cysteine 1629
Cysteine 1612 and cysteine 1747
Cysteine 1787 and cysteine 1804
Cysteine 1421 and cysteine 1438 L
Cysteine 1485 and cysteine 1502 L
Cysteine 1549 and cysteine 1566
Cysteine 1612 and cysteine 1629
Cysteine 1787 and cysteine 1790
Cysteine 1747 and cysteine 1749
Cysteine 1485 and cysteine 1488
Cysteine 1612 and cysteine 1615
Cysteine 1549 and cysteine 1552
Cysteine 1424 and cysteine 1438
Cysteine 1612 and cysteine 1749
Cysteine 1421 and cysteine 1424 L
Cysteine 1615 and cysteine 1629
Cysteine 1552 and cysteine 1566
Cysteine 1790 and cysteine 1804
Cysteine 1488 and cysteine 1502 L
Cysteine 1744 and cysteine 1749
Cysteine 1615 and cysteine 1747
Cysteine 188 and cysteine 206
A redox-regulated disulphide may form between two units of E3 SUMO-protein ligase RanBP2 at cysteines 3071 and 3213 (11 and 153 respectively in this structure).

Details

Redox score ?
79
PDB code
4i9y
Structure name
structure of the c-terminal domain of nup358
Structure deposition date
2012-12-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide A name
E3 SUMO-protein ligase RanBP2
Peptide B name
E3 SUMO-protein ligase RanBP2
Peptide A accession
P49792
Peptide B accession
P49792
Peptide A residue number
3071
Peptide B residue number
3213

Ligandability

Cysteine 3071 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 3213 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1549 and 1563.

Details

Redox score ?
93
PDB code
7mns
Structure name
crystal structure of the znf4 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
3
% buried
44
Peptide accession
P49792
Residue number A
1549
Residue number B
1563
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1549 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1563 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1787 and 1801.

Details

Redox score ?
93
PDB code
7mnv
Structure name
crystal structure of the znf8 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
59
Minimum pKa ?
3
% buried
41
Peptide accession
P49792
Residue number A
1787
Residue number B
1801
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1787 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1801 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1485 and 1499.

Details

Redox score ?
92
PDB code
7mnr
Structure name
crystal structure of the znf3 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
56
Minimum pKa ?
3
% buried
41
Peptide accession
P49792
Residue number A
1485
Residue number B
1499
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1485 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1499 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1421 and 1435.

Details

Redox score ?
92
PDB code
7mnp
Structure name
crystal structure of the znf2 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
3
% buried
44
Peptide accession
P49792
Residue number A
1421
Residue number B
1435
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1421 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 1435 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1790 and 1801.

Details

Redox score ?
90
PDB code
7mnv
Structure name
crystal structure of the znf8 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
75
Minimum pKa ?
3
% buried
60
Peptide accession
P49792
Residue number A
1790
Residue number B
1801
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1790 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1801 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1552 and 1563.

Details

Redox score ?
90
PDB code
7mns
Structure name
crystal structure of the znf4 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
75
Minimum pKa ?
3
% buried
60
Peptide accession
P49792
Residue number A
1552
Residue number B
1563
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1552 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1563 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1424 and 1435.

Details

Redox score ?
89
PDB code
7mnq
Structure name
crystal structure of the znf2 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
74
Minimum pKa ?
3
% buried
60
Peptide accession
P49792
Residue number A
1424
Residue number B
1435
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1424 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1435 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1563 and 1566.

Details

Redox score ?
89
PDB code
7mns
Structure name
crystal structure of the znf4 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
66
Minimum pKa ?
3
% buried
44
Peptide accession
P49792
Residue number A
1563
Residue number B
1566
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1563 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1566 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1488 and 1499.

Details

Redox score ?
89
PDB code
7mnr
Structure name
crystal structure of the znf3 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
74
Minimum pKa ?
3
% buried
58
Peptide accession
P49792
Residue number A
1488
Residue number B
1499
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1488 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1499 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1801 and 1804.

Details

Redox score ?
88
PDB code
7mnv
Structure name
crystal structure of the znf8 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
66
Minimum pKa ?
3
% buried
40
Peptide accession
P49792
Residue number A
1801
Residue number B
1804
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1801 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1804 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1435 and 1438.

Details

Redox score ?
88
PDB code
7mnq
Structure name
crystal structure of the znf2 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
65
Minimum pKa ?
3
% buried
42
Peptide accession
P49792
Residue number A
1435
Residue number B
1438
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1435 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1438 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1612 and 1744 (1730 and 1744 respectively in this structure).

Details

Redox score ?
87
PDB code
7mnu
Structure name
crystal structure of the znf7 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
6
% buried
39
Peptide accession
P49792
Residue number A
1612
Residue number B
1744
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1612 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1744 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1499 and 1502.

Details

Redox score ?
87
PDB code
7mnr
Structure name
crystal structure of the znf3 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
65
Minimum pKa ?
3
% buried
41
Peptide accession
P49792
Residue number A
1499
Residue number B
1502
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1499 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 1502 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1612 and 1626.

Details

Redox score ?
86
PDB code
7mnt
Structure name
crystal structure of the znf5 or znf6 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
56
Minimum pKa ?
6
% buried
40
Peptide accession
P49792
Residue number A
1612
Residue number B
1626
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1612 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1626 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1615 and 1744 (1733 and 1744 respectively in this structure).

Details

Redox score ?
84
PDB code
7mnu
Structure name
crystal structure of the znf7 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
75
Minimum pKa ?
6
% buried
56
Peptide accession
P49792
Residue number A
1615
Residue number B
1744
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1615 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1744 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1744 and 1747.

Details

Redox score ?
83
PDB code
7mnu
Structure name
crystal structure of the znf7 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
65
Minimum pKa ?
6
% buried
38
Peptide accession
P49792
Residue number A
1744
Residue number B
1747
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1744 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1747 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1615 and 1626.

Details

Redox score ?
83
PDB code
7mnt
Structure name
crystal structure of the znf5 or znf6 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
74
Minimum pKa ?
6
% buried
56
Peptide accession
P49792
Residue number A
1615
Residue number B
1626
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1615 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1626 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1626 and 1629.

Details

Redox score ?
81
PDB code
7mnt
Structure name
crystal structure of the znf5 or znf6 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
64
Minimum pKa ?
6
% buried
38
Peptide accession
P49792
Residue number A
1626
Residue number B
1629
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1626 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1629 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1612 and 1747 (1730 and 1747 respectively in this structure).

Details

Redox score ?
80
PDB code
7mnu
Structure name
crystal structure of the znf7 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
8
% buried
35
Peptide accession
P49792
Residue number A
1612
Residue number B
1747
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1612 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1747 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1787 and 1804.

Details

Redox score ?
80
PDB code
7mnv
Structure name
crystal structure of the znf8 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
63
Minimum pKa ?
8
% buried
37
Peptide accession
P49792
Residue number A
1787
Residue number B
1804
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1787 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1804 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1421 and 1438.

Details

Redox score ?
80
PDB code
7mnq
Structure name
crystal structure of the znf2 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
8
% buried
38
Peptide accession
P49792
Residue number A
1421
Residue number B
1438
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1421 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 1438 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1485 and 1502.

Details

Redox score ?
80
PDB code
7mnr
Structure name
crystal structure of the znf3 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
8
% buried
38
Peptide accession
P49792
Residue number A
1485
Residue number B
1502
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1485 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1502 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1549 and 1566.

Details

Redox score ?
80
PDB code
7mns
Structure name
crystal structure of the znf4 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
8
% buried
42
Peptide accession
P49792
Residue number A
1549
Residue number B
1566
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1549 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1566 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1612 and 1629.

Details

Redox score ?
79
PDB code
7mnt
Structure name
crystal structure of the znf5 or znf6 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
8
% buried
36
Peptide accession
P49792
Residue number A
1612
Residue number B
1629
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1612 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1629 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1787 and 1790.

Details

Redox score ?
79
PDB code
7mnv
Structure name
crystal structure of the znf8 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
73
Minimum pKa ?
8
% buried
56
Peptide accession
P49792
Residue number A
1787
Residue number B
1790
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1787 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1790 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1747 and 1749.

Details

Redox score ?
79
PDB code
7mnu
Structure name
crystal structure of the znf7 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
58
Minimum pKa ?
9
% buried
18
Peptide accession
P49792
Residue number A
1747
Residue number B
1749
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1747 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1749 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1485 and 1488.

Details

Redox score ?
78
PDB code
7mnr
Structure name
crystal structure of the znf3 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
72
Minimum pKa ?
8
% buried
56
Peptide accession
P49792
Residue number A
1485
Residue number B
1488
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1485 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1488 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1612 and 1615 (1730 and 1733 respectively in this structure).

Details

Redox score ?
78
PDB code
7mnu
Structure name
crystal structure of the znf7 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
71
Minimum pKa ?
8
% buried
54
Peptide accession
P49792
Residue number A
1612
Residue number B
1615
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1612 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1615 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1549 and 1552.

Details

Redox score ?
77
PDB code
7mns
Structure name
crystal structure of the znf4 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
72
Minimum pKa ?
8
% buried
58
Peptide accession
P49792
Residue number A
1549
Residue number B
1552
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1549 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1552 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1424 and 1438.

Details

Redox score ?
74
PDB code
7mnp
Structure name
crystal structure of the znf2 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
78
Minimum pKa ?
8
% buried
56
Peptide accession
P49792
Residue number A
1424
Residue number B
1438
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1424 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1438 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1612 and 1749 (1730 and 1749 respectively in this structure).

Details

Redox score ?
73
PDB code
7mnu
Structure name
crystal structure of the znf7 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
6
Half-sphere exposure sum ?
49
Minimum pKa ?
8
% buried
18
Peptide accession
P49792
Residue number A
1612
Residue number B
1749
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1612 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1749 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1421 and 1424.

Details

Redox score ?
73
PDB code
7mnp
Structure name
crystal structure of the znf2 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
71
Minimum pKa ?
10
% buried
59
Peptide accession
P49792
Residue number A
1421
Residue number B
1424
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1421 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 1424 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1615 and 1629.

Details

Redox score ?
72
PDB code
7mnt
Structure name
crystal structure of the znf5 or znf6 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
77
Minimum pKa ?
9
% buried
50
Peptide accession
P49792
Residue number A
1615
Residue number B
1629
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1615 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1629 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1552 and 1566.

Details

Redox score ?
70
PDB code
7mns
Structure name
crystal structure of the znf4 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
79
Minimum pKa ?
10
% buried
57
Peptide accession
P49792
Residue number A
1552
Residue number B
1566
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1552 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1566 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1790 and 1804.

Details

Redox score ?
69
PDB code
7mnv
Structure name
crystal structure of the znf8 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
79
Minimum pKa ?
10
% buried
56
Peptide accession
P49792
Residue number A
1790
Residue number B
1804
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1790 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1804 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1488 and 1502.

Details

Redox score ?
68
PDB code
7mnr
Structure name
crystal structure of the znf3 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
79
Minimum pKa ?
10
% buried
56
Peptide accession
P49792
Residue number A
1488
Residue number B
1502
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1488 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1502 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1744 and 1749.

Details

Redox score ?
68
PDB code
7mnu
Structure name
crystal structure of the znf7 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
7
Half-sphere exposure sum ?
55
Minimum pKa ?
6
% buried
22
Peptide accession
P49792
Residue number A
1744
Residue number B
1749
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1744 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1749 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 1615 and 1747 (1733 and 1747 respectively in this structure).

Details

Redox score ?
66
PDB code
7mnu
Structure name
crystal structure of the znf7 of nucleoporin nup358/ranbp2 in complex with ran-gdp
Structure deposition date
2021-05-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
78
Minimum pKa ?
11
% buried
52
Peptide accession
P49792
Residue number A
1615
Residue number B
1747
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 1615 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1747 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within E3 SUMO-protein ligase RanBP2 between cysteines 188 and 206.

Details

Redox score ?
64
PDB code
7mnj
Structure name
crystal structure of the n-terminal domain of nup358/ranbp2 (residues 145-673)
Structure deposition date
2021-05-01
Thiol separation (Å)
5
Half-sphere exposure sum ?
77
Minimum pKa ?
8
% buried
100
Peptide accession
P49792
Residue number A
188
Residue number B
206
Peptide name
E3 SUMO-protein ligase RanBP2

Ligandability

Cysteine 188 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 206 of E3 SUMO-protein ligase RanBP2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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