Cytosolic purine 5'-nucleotidase
Intramolecular
Cysteine 48 and cysteine 336 L
5cr7 A 48 A 336
A redox-regulated disulphide may form within Cytosolic purine 5'-nucleotidase between cysteines 48 and 336. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
5cr7
Structure name
human cytosolic 5'-nucleotidase ii in complex with n-(9h-purin-6-yl)- 3-(3-pyrrol-1-ylphenyl)benzamide
Structure deposition date
2015-07-22
Thiol separation (Å)
8
Half-sphere exposure sum ?
68
Minimum pKa ?
10
% buried
54
Peptide accession
P49902
Residue number A
48
Residue number B
336
Peptide name
Cytosolic purine 5'-nucleotidase
Ligandability
Cysteine 48 of Cytosolic purine 5'-nucleotidase
Cysteine 336 of Cytosolic purine 5'-nucleotidase
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