ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

PDZ and LIM domain protein 4

Intermolecular
Cysteine 72 and cysteine 72
Cysteine 44 and cysteine 44
A redox-regulated disulphide may form between two units of PDZ and LIM domain protein 4 at cysteines 72 and 72.

Details

Redox score ?
90
PDB code
4q2o
Structure name
pdlim4 pdz in complex with a phage-derived peptide
Structure deposition date
2014-04-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide A name
PDZ and LIM domain protein 4
Peptide B name
PDZ and LIM domain protein 4
Peptide A accession
P50479
Peptide B accession
P50479
Peptide A residue number
72
Peptide B residue number
72

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form between two units of PDZ and LIM domain protein 4 at cysteines 44 and 44.

Details

Redox score ?
77
PDB code
4q2o
Structure name
pdlim4 pdz in complex with a phage-derived peptide
Structure deposition date
2014-04-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
89
Minimum pKa ?
nan
% buried
nan
Peptide A name
PDZ and LIM domain protein 4
Peptide B name
PDZ and LIM domain protein 4
Peptide A accession
P50479
Peptide B accession
P50479
Peptide A residue number
44
Peptide B residue number
44

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: