ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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ETS domain-containing transcription factor ERF

Intermolecular
Cysteine 72 and cysteine 72
A redox-regulated disulphide may form between two units of ETS domain-containing transcription factor ERF at cysteines 72 and 72.

Details

Redox score ?
86
PDB code
7jsl
Structure name
crystal structure of the dna binding domain of human transcription factor erf in the oxidized form, in complex with double-stranded dna accggaagtg
Structure deposition date
2020-08-14
Thiol separation (Å)
2
Half-sphere exposure sum ?
38
Minimum pKa ?
nan
% buried
nan
Peptide A name
ETS domain-containing transcription factor ERF
Peptide B name
ETS domain-containing transcription factor ERF
Peptide A accession
P50548
Peptide B accession
P50548
Peptide A residue number
72
Peptide B residue number
72

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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