ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Tumor necrosis factor ligand superfamily member 10

Intermolecular
Cysteine 230 and cysteine 230
A redox-regulated disulphide may form between two units of Tumor necrosis factor ligand superfamily member 10 at cysteines 230 and 230.

Details

Redox score ?
81
PDB code
5cir
Structure name
crystal structure of death receptor 4 (dr4; tnffrsf10a) bound to trail (tnfsf10)
Structure deposition date
2015-07-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
86
Minimum pKa ?
2
% buried
92
Peptide A name
Tumor necrosis factor ligand superfamily member 10
Peptide B name
Tumor necrosis factor ligand superfamily member 10
Peptide A accession
P50591
Peptide B accession
P50591
Peptide A residue number
230
Peptide B residue number
230

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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