ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Basal cell adhesion molecule

Intramolecular
Cysteine 53 and cysteine 125
Cysteine 172 and cysteine 237
A redox-regulated disulphide may form within Basal cell adhesion molecule between cysteines 53 and 125 (22 and 94 respectively in this structure).

Details

Redox score ?
83
PDB code
2pf6
Structure name
lutheran glycoprotein, n-terminal domains 1 and 2
Structure deposition date
2007-04-04
Thiol separation (Å)
2
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
P50895
Residue number A
53
Residue number B
125
Peptide name
Basal cell adhesion molecule

Ligandability

Cysteine 53 of Basal cell adhesion molecule

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 125 of Basal cell adhesion molecule

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Basal cell adhesion molecule between cysteines 172 and 237 (141 and 206 respectively in this structure).

Details

Redox score ?
79
PDB code
2pf6
Structure name
lutheran glycoprotein, n-terminal domains 1 and 2
Structure deposition date
2007-04-04
Thiol separation (Å)
2
Half-sphere exposure sum ?
87
Minimum pKa ?
nan
% buried
nan
Peptide accession
P50895
Residue number A
172
Residue number B
237
Peptide name
Basal cell adhesion molecule

Ligandability

Cysteine 172 of Basal cell adhesion molecule

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 237 of Basal cell adhesion molecule

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: