ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Probable global transcription activator SNF2L2

Intramolecular
Cysteine 861 and cysteine 906 L
A redox-regulated disulphide may form within Probable global transcription activator SNF2L2 between cysteines 861 and 906. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
47
PDB code
6eg2
Structure name
crystal structure of human brm in complex with compound 16
Structure deposition date
2018-08-17
Thiol separation (Å)
9
Half-sphere exposure sum ?
47
Minimum pKa ?
10
% buried
32
Peptide accession
P51531
Residue number A
861
Residue number B
906
Peptide name
Probable global transcription activator SNF2L2

Ligandability

Cysteine 861 of Probable global transcription activator SNF2L2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 906 of Probable global transcription activator SNF2L2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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