a tool for identifying drug-targetable redox-active disulphides

Translocon-associated protein subunit delta

Intramolecular

Cysteine 26 and cysteine 57

A redox-regulated disulphide may form within Translocon-associated protein subunit delta between cysteines 26 and 57.

Details

Redox score ?

89

PDB code

Structure name

subtomogram average of the human sec61-trap-osta-translocon

Structure deposition date

2022-09-27

Thiol separation (Å)

2

Half-sphere exposure sum ?

46

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

26

Residue number B

57

Peptide name

Translocon-associated protein subunit delta

Ligandability

Cysteine 26 of Translocon-associated protein subunit delta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 57 of Translocon-associated protein subunit delta

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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