C-C chemokine receptor type 5
Intermolecular
Cysteine 20 and cysteine 33 of C-C motif chemokine 5
Cysteine 269 and cysteine 33 of C-C motif chemokine 5
Cysteine 20 and cysteine 57 of C-C motif chemokine 5
Cysteine 20 and cysteine 34 of C-C motif chemokine 5
Cysteine 20 and cysteine 73 of C-C motif chemokine 5
Cysteine 269 and cysteine 73 of C-C motif chemokine 5
Intramolecular
Cysteine 20 and cysteine 269
Cysteine 101 and cysteine 178
Cysteine 10 and cysteine 20
Cysteine 290 and cysteine 20
More...Cysteine 20 and cysteine 20
Cysteine 290 and cysteine 269
Cysteine 291 and cysteine 20
Cysteine 178 and cysteine 213
Cysteine 20 and cysteine 213
Cysteine 178 and cysteine 20
Cysteine 290 and cysteine 291
Cysteine 291 and cysteine 269
Cysteine 291 and cysteine 15
Cysteine 291 and cysteine 50
Cysteine 20 and cysteine 1039
Cysteine 178 and cysteine 1039
Cysteine 290 and cysteine -46
Cysteine 11 and cysteine 291
Cysteine 15 and cysteine 269
Cysteine 10 and cysteine 291
Cysteine 28 and cysteine 267
Cysteine -81 and cysteine 16
Cysteine 1039 and cysteine 213
Cysteine 50 and cysteine 269
5uiw A 20 B 10
A redox-regulated disulphide may form between cysteine 20 of C-C chemokine receptor type 5 and cysteine 33 of C-C motif chemokine 5 (20 and 10 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
5uiw
Structure name
crystal structure of cc chemokine receptor 5 (ccr5) in complex with high potency hiv entry inhibitor 5p7-ccl5
Structure deposition date
2017-01-15
Thiol separation (Å)
7
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C chemokine receptor type 5
Peptide B name
C-C motif chemokine 5
Peptide A accession
P51681
Peptide B accession
P13501
Peptide A residue number
20
Peptide B residue number
33
Ligandability
Cysteine 20 of C-C chemokine receptor type 5
Cysteine 33 of C-C motif chemokine 5
5uiw A 269 B 10
A redox-regulated disulphide may form between cysteine 269 of C-C chemokine receptor type 5 and cysteine 33 of C-C motif chemokine 5 (269 and 10 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
5uiw
Structure name
crystal structure of cc chemokine receptor 5 (ccr5) in complex with high potency hiv entry inhibitor 5p7-ccl5
Structure deposition date
2017-01-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C chemokine receptor type 5
Peptide B name
C-C motif chemokine 5
Peptide A accession
P51681
Peptide B accession
P13501
Peptide A residue number
269
Peptide B residue number
33
Ligandability
Cysteine 269 of C-C chemokine receptor type 5
Cysteine 33 of C-C motif chemokine 5
5uiw A 20 B 34
A redox-regulated disulphide may form between cysteine 20 of C-C chemokine receptor type 5 and cysteine 57 of C-C motif chemokine 5 (20 and 34 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
5uiw
Structure name
crystal structure of cc chemokine receptor 5 (ccr5) in complex with high potency hiv entry inhibitor 5p7-ccl5
Structure deposition date
2017-01-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C chemokine receptor type 5
Peptide B name
C-C motif chemokine 5
Peptide A accession
P51681
Peptide B accession
P13501
Peptide A residue number
20
Peptide B residue number
57
Ligandability
Cysteine 20 of C-C chemokine receptor type 5
Cysteine 57 of C-C motif chemokine 5
5uiw A 20 B 11
A redox-regulated disulphide may form between cysteine 20 of C-C chemokine receptor type 5 and cysteine 34 of C-C motif chemokine 5 (20 and 11 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
5uiw
Structure name
crystal structure of cc chemokine receptor 5 (ccr5) in complex with high potency hiv entry inhibitor 5p7-ccl5
Structure deposition date
2017-01-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C chemokine receptor type 5
Peptide B name
C-C motif chemokine 5
Peptide A accession
P51681
Peptide B accession
P13501
Peptide A residue number
20
Peptide B residue number
34
Ligandability
Cysteine 20 of C-C chemokine receptor type 5
Cysteine 34 of C-C motif chemokine 5
5uiw A 20 B 50
A redox-regulated disulphide may form between cysteine 20 of C-C chemokine receptor type 5 and cysteine 73 of C-C motif chemokine 5 (20 and 50 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
5uiw
Structure name
crystal structure of cc chemokine receptor 5 (ccr5) in complex with high potency hiv entry inhibitor 5p7-ccl5
Structure deposition date
2017-01-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C chemokine receptor type 5
Peptide B name
C-C motif chemokine 5
Peptide A accession
P51681
Peptide B accession
P13501
Peptide A residue number
20
Peptide B residue number
73
Ligandability
Cysteine 20 of C-C chemokine receptor type 5
Cysteine 73 of C-C motif chemokine 5
5uiw A 269 B 50
A redox-regulated disulphide may form between cysteine 269 of C-C chemokine receptor type 5 and cysteine 73 of C-C motif chemokine 5 (269 and 50 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
5uiw
Structure name
crystal structure of cc chemokine receptor 5 (ccr5) in complex with high potency hiv entry inhibitor 5p7-ccl5
Structure deposition date
2017-01-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C chemokine receptor type 5
Peptide B name
C-C motif chemokine 5
Peptide A accession
P51681
Peptide B accession
P13501
Peptide A residue number
269
Peptide B residue number
73
Ligandability
Cysteine 269 of C-C chemokine receptor type 5
Cysteine 73 of C-C motif chemokine 5
4mbs A 20 A 269
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 20 and 269.
Details
Redox score ?
88
PDB code
4mbs
Structure name
crystal structure of the ccr5 chemokine receptor
Structure deposition date
2013-08-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
29
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
20
Residue number B
269
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 20 of C-C chemokine receptor type 5
Cysteine 269 of C-C chemokine receptor type 5
6akx B 101 B 178
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 101 and 178.
Details
Redox score ?
85
PDB code
6akx
Structure name
the crystal structure of human chemokine receptor ccr5 in complex with compound 21
Structure deposition date
2018-09-04
Thiol separation (Å)
2
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
101
Residue number B
178
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 101 of C-C chemokine receptor type 5
Cysteine 178 of C-C chemokine receptor type 5
7f1r R 10 R 34
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 10 and 20 (10 and 34 respectively in this structure).
Details
Redox score ?
81
PDB code
7f1r
Structure name
cryo-em structure of the chemokine receptor ccr5 in complex with rantes and gi
Structure deposition date
2021-06-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
10
Residue number B
20
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 10 of C-C chemokine receptor type 5
Cysteine 20 of C-C chemokine receptor type 5
Cysteine 10 in protein A could not be asigned to a Uniprot residue.
7f1t A -86 A 20
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 290 and 20 (-86 and 20 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
7f1t
Structure name
crystal structure of the human chemokine receptor ccr5 in complex with mip-1a
Structure deposition date
2021-06-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
290
Residue number B
20
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 290 of C-C chemokine receptor type 5
Cysteine 20 of C-C chemokine receptor type 5
Uncertain whether structure cysteine -86 has been assigned to correct residue.
7f1t A -62 A 20
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 20 and 20 (-62 and 20 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
7f1t
Structure name
crystal structure of the human chemokine receptor ccr5 in complex with mip-1a
Structure deposition date
2021-06-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
20
Residue number B
20
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 20 of C-C chemokine receptor type 5
Cysteine 20 of C-C chemokine receptor type 5
7f1t A -86 A 269
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 290 and 269 (-86 and 269 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
7f1t
Structure name
crystal structure of the human chemokine receptor ccr5 in complex with mip-1a
Structure deposition date
2021-06-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
290
Residue number B
269
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 290 of C-C chemokine receptor type 5
Cysteine 269 of C-C chemokine receptor type 5
Uncertain whether structure cysteine -86 has been assigned to correct residue.
7f1t A -85 A 20
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 291 and 20 (-85 and 20 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
7f1t
Structure name
crystal structure of the human chemokine receptor ccr5 in complex with mip-1a
Structure deposition date
2021-06-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
291
Residue number B
20
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 291 of C-C chemokine receptor type 5
Cysteine 20 of C-C chemokine receptor type 5
Uncertain whether structure cysteine -85 has been assigned to correct residue.
5uiw A 1006 A 1042
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 178 and 213 (1006 and 1042 respectively in this structure).
Details
Redox score ?
nan
PDB code
5uiw
Structure name
crystal structure of cc chemokine receptor 5 (ccr5) in complex with high potency hiv entry inhibitor 5p7-ccl5
Structure deposition date
2017-01-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
46
Minimum pKa ?
6
% buried
0
Peptide accession
P51681
Residue number A
178
Residue number B
213
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 178 of C-C chemokine receptor type 5
Cysteine 213 of C-C chemokine receptor type 5
Uncertain whether structure cysteine 1006 has been assigned to correct residue.
Uncertain whether structure cysteine 1042 has been assigned to correct residue.
6akx A 1009 A 1042
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 20 and 213 (1009 and 1042 respectively in this structure).
Details
Redox score ?
nan
PDB code
6akx
Structure name
the crystal structure of human chemokine receptor ccr5 in complex with compound 21
Structure deposition date
2018-09-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
38
Minimum pKa ?
6
% buried
0
Peptide accession
P51681
Residue number A
20
Residue number B
213
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 20 of C-C chemokine receptor type 5
Cysteine 213 of C-C chemokine receptor type 5
Uncertain whether structure cysteine 1009 has been assigned to correct residue.
Uncertain whether structure cysteine 1042 has been assigned to correct residue.
7f1t A 1006 A 1009
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 178 and 20 (1006 and 1009 respectively in this structure).
Details
Redox score ?
nan
PDB code
7f1t
Structure name
crystal structure of the human chemokine receptor ccr5 in complex with mip-1a
Structure deposition date
2021-06-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
49
Minimum pKa ?
10
% buried
0
Peptide accession
P51681
Residue number A
178
Residue number B
20
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 178 of C-C chemokine receptor type 5
Cysteine 20 of C-C chemokine receptor type 5
Uncertain whether structure cysteine 1006 has been assigned to correct residue.
Uncertain whether structure cysteine 1009 has been assigned to correct residue.
7f1t A -86 A -85
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 290 and 291 (-86 and -85 respectively in this structure).
Details
Redox score ?
nan
PDB code
7f1t
Structure name
crystal structure of the human chemokine receptor ccr5 in complex with mip-1a
Structure deposition date
2021-06-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
290
Residue number B
291
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 290 of C-C chemokine receptor type 5
Cysteine 291 of C-C chemokine receptor type 5
Uncertain whether structure cysteine -86 has been assigned to correct residue.
Uncertain whether structure cysteine -85 has been assigned to correct residue.
7f1q R 11 R 112
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 291 and 269 (11 and 112 respectively in this structure).
Details
Redox score ?
nan
PDB code
7f1q
Structure name
cryo-em structure of the chemokine receptor ccr5 in complex with mip- 1a and gi
Structure deposition date
2021-06-09
Thiol separation (Å)
10
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
291
Residue number B
269
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 291 of C-C chemokine receptor type 5
Cysteine 269 of C-C chemokine receptor type 5
Uncertain whether structure cysteine 11 has been assigned to correct residue.
Uncertain whether structure cysteine 112 has been assigned to correct residue.
7f1q R 11 R 15
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 291 and 15 (11 and 15 respectively in this structure).
Details
Redox score ?
nan
PDB code
7f1q
Structure name
cryo-em structure of the chemokine receptor ccr5 in complex with mip- 1a and gi
Structure deposition date
2021-06-09
Thiol separation (Å)
8
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
291
Residue number B
15
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 291 of C-C chemokine receptor type 5
Cysteine 15 of C-C chemokine receptor type 5
Uncertain whether structure cysteine 11 has been assigned to correct residue.
Cysteine 15 in protein B could not be asigned to a Uniprot residue.
7f1q R 11 R 50
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 291 and 50 (11 and 50 respectively in this structure).
Details
Redox score ?
nan
PDB code
7f1q
Structure name
cryo-em structure of the chemokine receptor ccr5 in complex with mip- 1a and gi
Structure deposition date
2021-06-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
291
Residue number B
50
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 291 of C-C chemokine receptor type 5
Cysteine 50 of C-C chemokine receptor type 5
Uncertain whether structure cysteine 11 has been assigned to correct residue.
Cysteine 50 in protein B could not be asigned to a Uniprot residue.
4mbs B 1009 B 1039
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 20 and 1039 (1009 and 1039 respectively in this structure).
Details
Redox score ?
nan
PDB code
4mbs
Structure name
crystal structure of the ccr5 chemokine receptor
Structure deposition date
2013-08-19
Thiol separation (Å)
3
Half-sphere exposure sum ?
48
Minimum pKa ?
7
% buried
3
Peptide accession
P51681
Residue number A
20
Residue number B
1039
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 20 of C-C chemokine receptor type 5
Cysteine 1039 of C-C chemokine receptor type 5
Uncertain whether structure cysteine 1009 has been assigned to correct residue.
Cysteine 1039 in protein B could not be asigned to a Uniprot residue.
6aky A 1006 A 1039
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 178 and 1039 (1006 and 1039 respectively in this structure).
Details
Redox score ?
nan
PDB code
6aky
Structure name
the crystal structure of human chemokine receptor ccr5 in complex with compound 34
Structure deposition date
2018-09-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
6
% buried
3
Peptide accession
P51681
Residue number A
178
Residue number B
1039
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 178 of C-C chemokine receptor type 5
Cysteine 1039 of C-C chemokine receptor type 5
Uncertain whether structure cysteine 1006 has been assigned to correct residue.
Cysteine 1039 in protein B could not be asigned to a Uniprot residue.
7f1t A -86 A -46
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 290 and -46 (-86 and -46 respectively in this structure).
Details
Redox score ?
nan
PDB code
7f1t
Structure name
crystal structure of the human chemokine receptor ccr5 in complex with mip-1a
Structure deposition date
2021-06-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
290
Residue number B
-46
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 290 of C-C chemokine receptor type 5
Cysteine -46 of C-C chemokine receptor type 5
Uncertain whether structure cysteine -86 has been assigned to correct residue.
Cysteine -46 in protein B could not be asigned to a Uniprot residue.
7f1r R 11 R 50
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 11 and 291 (11 and 50 respectively in this structure).
Details
Redox score ?
nan
PDB code
7f1r
Structure name
cryo-em structure of the chemokine receptor ccr5 in complex with rantes and gi
Structure deposition date
2021-06-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
11
Residue number B
291
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 11 of C-C chemokine receptor type 5
Cysteine 291 of C-C chemokine receptor type 5
Cysteine 11 in protein A could not be asigned to a Uniprot residue.
Uncertain whether structure cysteine 50 has been assigned to correct residue.
7f1q R 15 R 112
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 15 and 269 (15 and 112 respectively in this structure).
Details
Redox score ?
nan
PDB code
7f1q
Structure name
cryo-em structure of the chemokine receptor ccr5 in complex with mip- 1a and gi
Structure deposition date
2021-06-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
15
Residue number B
269
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 15 of C-C chemokine receptor type 5
Cysteine 269 of C-C chemokine receptor type 5
Cysteine 15 in protein A could not be asigned to a Uniprot residue.
Uncertain whether structure cysteine 112 has been assigned to correct residue.
7f1r R 10 R 50
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 10 and 291 (10 and 50 respectively in this structure).
Details
Redox score ?
nan
PDB code
7f1r
Structure name
cryo-em structure of the chemokine receptor ccr5 in complex with rantes and gi
Structure deposition date
2021-06-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
10
Residue number B
291
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 10 of C-C chemokine receptor type 5
Cysteine 291 of C-C chemokine receptor type 5
Cysteine 10 in protein A could not be asigned to a Uniprot residue.
Uncertain whether structure cysteine 50 has been assigned to correct residue.
7f1r R 28 R 267
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 28 and 267.
Details
Redox score ?
nan
PDB code
7f1r
Structure name
cryo-em structure of the chemokine receptor ccr5 in complex with rantes and gi
Structure deposition date
2021-06-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
28
Residue number B
267
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 28 of C-C chemokine receptor type 5
Cysteine 267 of C-C chemokine receptor type 5
Cysteine 28 in protein A could not be asigned to a Uniprot residue.
Cysteine 267 in protein B could not be asigned to a Uniprot residue.
7f1t A -81 A 16
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines -81 and 16.
Details
Redox score ?
nan
PDB code
7f1t
Structure name
crystal structure of the human chemokine receptor ccr5 in complex with mip-1a
Structure deposition date
2021-06-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
-81
Residue number B
16
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine -81 of C-C chemokine receptor type 5
Cysteine 16 of C-C chemokine receptor type 5
Cysteine -81 in protein A could not be asigned to a Uniprot residue.
Cysteine 16 in protein B could not be asigned to a Uniprot residue.
4mbs B 1039 B 1042
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 1039 and 213 (1039 and 1042 respectively in this structure).
Details
Redox score ?
nan
PDB code
4mbs
Structure name
crystal structure of the ccr5 chemokine receptor
Structure deposition date
2013-08-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
7
% buried
3
Peptide accession
P51681
Residue number A
1039
Residue number B
213
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 1039 of C-C chemokine receptor type 5
Cysteine 213 of C-C chemokine receptor type 5
Cysteine 1039 in protein A could not be asigned to a Uniprot residue.
Uncertain whether structure cysteine 1042 has been assigned to correct residue.
7f1q R 50 R 112
A redox-regulated disulphide may form within C-C chemokine receptor type 5 between cysteines 50 and 269 (50 and 112 respectively in this structure).
Details
Redox score ?
nan
PDB code
7f1q
Structure name
cryo-em structure of the chemokine receptor ccr5 in complex with mip- 1a and gi
Structure deposition date
2021-06-09
Thiol separation (Å)
8
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51681
Residue number A
50
Residue number B
269
Peptide name
C-C chemokine receptor type 5
Ligandability
Cysteine 50 of C-C chemokine receptor type 5
Cysteine 269 of C-C chemokine receptor type 5
Cysteine 50 in protein A could not be asigned to a Uniprot residue.
Uncertain whether structure cysteine 112 has been assigned to correct residue.
If this tool was useful for finding a disulphide, please cite: