C-C chemokine receptor type 6
Intermolecular
Cysteine 33 of C-C motif chemokine 20 and cysteine 36
Cysteine 32 of C-C motif chemokine 20 and cysteine 36
Cysteine 74 of C-C motif chemokine 20 and cysteine 36
Cysteine 33 of C-C motif chemokine 20 and cysteine 288
Intramolecular
Cysteine 36 and cysteine 288
Cysteine 118 and cysteine 197
Cysteine 138 and cysteine 168
Cysteine 309 and cysteine 310
Cysteine 131 and cysteine 168
Cysteine 57 and cysteine 310
More...Cysteine 266 and cysteine 310
Cysteine 131 and cysteine 138
6wwz C 7 R 36
A redox-regulated disulphide may form between cysteine 33 of C-C motif chemokine 20 and cysteine 36 of C-C chemokine receptor type 6 (7 and 36 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
6wwz
Structure name
cryo-em structure of the human chemokine receptor ccr6 in complex with ccl20 and a go protein
Structure deposition date
2020-05-09
Thiol separation (Å)
8
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C motif chemokine 20
Peptide B name
C-C chemokine receptor type 6
Peptide A accession
P78556
Peptide B accession
P51684
Peptide A residue number
33
Peptide B residue number
36
Ligandability
Cysteine 33 of C-C motif chemokine 20
Cysteine 36 of C-C chemokine receptor type 6
6wwz C 6 R 36
A redox-regulated disulphide may form between cysteine 32 of C-C motif chemokine 20 and cysteine 36 of C-C chemokine receptor type 6 (6 and 36 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
6wwz
Structure name
cryo-em structure of the human chemokine receptor ccr6 in complex with ccl20 and a go protein
Structure deposition date
2020-05-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C motif chemokine 20
Peptide B name
C-C chemokine receptor type 6
Peptide A accession
P78556
Peptide B accession
P51684
Peptide A residue number
32
Peptide B residue number
36
Ligandability
Cysteine 32 of C-C motif chemokine 20
Cysteine 36 of C-C chemokine receptor type 6
6wwz C 48 R 36
A redox-regulated disulphide may form between cysteine 74 of C-C motif chemokine 20 and cysteine 36 of C-C chemokine receptor type 6 (48 and 36 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
6wwz
Structure name
cryo-em structure of the human chemokine receptor ccr6 in complex with ccl20 and a go protein
Structure deposition date
2020-05-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C motif chemokine 20
Peptide B name
C-C chemokine receptor type 6
Peptide A accession
P78556
Peptide B accession
P51684
Peptide A residue number
74
Peptide B residue number
36
Ligandability
Cysteine 74 of C-C motif chemokine 20
Cysteine 36 of C-C chemokine receptor type 6
6wwz C 7 R 288
A redox-regulated disulphide may form between cysteine 33 of C-C motif chemokine 20 and cysteine 288 of C-C chemokine receptor type 6 (7 and 288 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
6wwz
Structure name
cryo-em structure of the human chemokine receptor ccr6 in complex with ccl20 and a go protein
Structure deposition date
2020-05-09
Thiol separation (Å)
10
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C motif chemokine 20
Peptide B name
C-C chemokine receptor type 6
Peptide A accession
P78556
Peptide B accession
P51684
Peptide A residue number
33
Peptide B residue number
288
Ligandability
Cysteine 33 of C-C motif chemokine 20
Cysteine 288 of C-C chemokine receptor type 6
6wwz R 36 R 288
A redox-regulated disulphide may form within C-C chemokine receptor type 6 between cysteines 36 and 288.
Details
Redox score ?
87
PDB code
6wwz
Structure name
cryo-em structure of the human chemokine receptor ccr6 in complex with ccl20 and a go protein
Structure deposition date
2020-05-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51684
Residue number A
36
Residue number B
288
Peptide name
C-C chemokine receptor type 6
Ligandability
Cysteine 36 of C-C chemokine receptor type 6
Cysteine 288 of C-C chemokine receptor type 6
6wwz R 118 R 197
A redox-regulated disulphide may form within C-C chemokine receptor type 6 between cysteines 118 and 197.
Details
Redox score ?
83
PDB code
6wwz
Structure name
cryo-em structure of the human chemokine receptor ccr6 in complex with ccl20 and a go protein
Structure deposition date
2020-05-09
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P51684
Residue number A
118
Residue number B
197
Peptide name
C-C chemokine receptor type 6
Ligandability
Cysteine 118 of C-C chemokine receptor type 6
Cysteine 197 of C-C chemokine receptor type 6
6wwz R 138 R 168
A redox-regulated disulphide may form within C-C chemokine receptor type 6 between cysteines 138 and 168. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
6wwz
Structure name
cryo-em structure of the human chemokine receptor ccr6 in complex with ccl20 and a go protein
Structure deposition date
2020-05-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
63
Minimum pKa ?
10
% buried
48
Peptide accession
P51684
Residue number A
138
Residue number B
168
Peptide name
C-C chemokine receptor type 6
Ligandability
Cysteine 138 of C-C chemokine receptor type 6
Cysteine 168 of C-C chemokine receptor type 6
6wwz R 309 R 310
A redox-regulated disulphide may form within C-C chemokine receptor type 6 between cysteines 309 and 310. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
6wwz
Structure name
cryo-em structure of the human chemokine receptor ccr6 in complex with ccl20 and a go protein
Structure deposition date
2020-05-09
Thiol separation (Å)
7
Half-sphere exposure sum ?
77
Minimum pKa ?
11
% buried
79
Peptide accession
P51684
Residue number A
309
Residue number B
310
Peptide name
C-C chemokine receptor type 6
Ligandability
Cysteine 309 of C-C chemokine receptor type 6
Cysteine 310 of C-C chemokine receptor type 6
6wwz R 131 R 168
A redox-regulated disulphide may form within C-C chemokine receptor type 6 between cysteines 131 and 168. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
6wwz
Structure name
cryo-em structure of the human chemokine receptor ccr6 in complex with ccl20 and a go protein
Structure deposition date
2020-05-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
69
Minimum pKa ?
10
% buried
44
Peptide accession
P51684
Residue number A
131
Residue number B
168
Peptide name
C-C chemokine receptor type 6
Ligandability
Cysteine 131 of C-C chemokine receptor type 6
Cysteine 168 of C-C chemokine receptor type 6
6wwz R 57 R 310
A redox-regulated disulphide may form within C-C chemokine receptor type 6 between cysteines 57 and 310. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
6wwz
Structure name
cryo-em structure of the human chemokine receptor ccr6 in complex with ccl20 and a go protein
Structure deposition date
2020-05-09
Thiol separation (Å)
10
Half-sphere exposure sum ?
73
Minimum pKa ?
10
% buried
42
Peptide accession
P51684
Residue number A
57
Residue number B
310
Peptide name
C-C chemokine receptor type 6
Ligandability
Cysteine 57 of C-C chemokine receptor type 6
Cysteine 310 of C-C chemokine receptor type 6
6wwz R 266 R 310
A redox-regulated disulphide may form within C-C chemokine receptor type 6 between cysteines 266 and 310. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
6wwz
Structure name
cryo-em structure of the human chemokine receptor ccr6 in complex with ccl20 and a go protein
Structure deposition date
2020-05-09
Thiol separation (Å)
10
Half-sphere exposure sum ?
67
Minimum pKa ?
10
% buried
42
Peptide accession
P51684
Residue number A
266
Residue number B
310
Peptide name
C-C chemokine receptor type 6
Ligandability
Cysteine 266 of C-C chemokine receptor type 6
Cysteine 310 of C-C chemokine receptor type 6
6wwz R 131 R 138
A redox-regulated disulphide may form within C-C chemokine receptor type 6 between cysteines 131 and 138. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
35
PDB code
6wwz
Structure name
cryo-em structure of the human chemokine receptor ccr6 in complex with ccl20 and a go protein
Structure deposition date
2020-05-09
Thiol separation (Å)
9
Half-sphere exposure sum ?
70
Minimum pKa ?
11
% buried
60
Peptide accession
P51684
Residue number A
131
Residue number B
138
Peptide name
C-C chemokine receptor type 6
Ligandability
Cysteine 131 of C-C chemokine receptor type 6
Cysteine 138 of C-C chemokine receptor type 6
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