ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Signal transducer and activator of transcription 5B

Intramolecular
Cysteine 400 and cysteine 401
A redox-regulated disulphide may form within Signal transducer and activator of transcription 5B between cysteines 400 and 401. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
52
PDB code
6mbw
Structure name
structure of transcription factor
Structure deposition date
2018-08-30
Thiol separation (Å)
8
Half-sphere exposure sum ?
52
Minimum pKa ?
9
% buried
18
Peptide accession
P51692
Residue number A
400
Residue number B
401
Peptide name
Signal transducer and activator of transcription 5B

Ligandability

Cysteine 400 of Signal transducer and activator of transcription 5B

Cysteine 401 of Signal transducer and activator of transcription 5B

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