Serine/threonine-protein kinase Nek2

Intramolecular

A redox-regulated disulphide may form within Serine/threonine-protein kinase Nek2 between cysteines 22 and 89. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

2w5h

Structure name

human nek2 kinase apo

Structure deposition date

2008-12-10

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

P51955

Residue number A

Residue number B

Peptide name

Serine/threonine-protein kinase Nek2

Ligandability

Cysteine 22 of Serine/threonine-protein kinase Nek2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.