ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Heterogeneous nuclear ribonucleoprotein M

Intramolecular
Cysteine 676 and cysteine 709
A redox-regulated disulphide may form within Heterogeneous nuclear ribonucleoprotein M between cysteines 676 and 709 (561 and 594 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
44
PDB code
2dh9
Structure name
solution structure of the c-terminal rna binding domain in heterogeneous nuclear ribonucleoprotein m
Structure deposition date
2006-03-23
Thiol separation (Å)
9
Half-sphere exposure sum ?
58
Minimum pKa ?
10
% buried
32
Peptide accession
P52272
Residue number A
676
Residue number B
709
Peptide name
Heterogeneous nuclear ribonucleoprotein M

Ligandability

Cysteine 676 of Heterogeneous nuclear ribonucleoprotein M

Cysteine 709 of Heterogeneous nuclear ribonucleoprotein M

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