ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Nuclear cap-binding protein subunit 2

Intramolecular
Cysteine 81 and cysteine 84
A redox-regulated disulphide may form within Nuclear cap-binding protein subunit 2 between cysteines 81 and 84. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
52
PDB code
1h6k
Structure name
nuclear cap binding complex
Structure deposition date
2001-06-18
Thiol separation (Å)
9
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
44
Peptide accession
P52298
Residue number A
81
Residue number B
84
Peptide name
Nuclear cap-binding protein subunit 2

Ligandability

Cysteine 81 of Nuclear cap-binding protein subunit 2

Cysteine 84 of Nuclear cap-binding protein subunit 2

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