ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Arf-GAP domain and FG repeat-containing protein 1

Intramolecular
Cysteine 32 and cysteine 52
Cysteine 29 and cysteine 52
Cysteine 29 and cysteine 32
Cysteine 32 and cysteine 49
Cysteine 49 and cysteine 52
Cysteine 29 and cysteine 49
A redox-regulated disulphide may form within Arf-GAP domain and FG repeat-containing protein 1 between cysteines 32 and 52.

Details

Redox score ?
72
PDB code
2olm
Structure name
arfgap domain of hiv-1 rev binding protein
Structure deposition date
2007-01-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
P52594
Residue number A
32
Residue number B
52
Peptide name
Arf-GAP domain and FG repeat-containing protein 1

Ligandability

Cysteine 32 of Arf-GAP domain and FG repeat-containing protein 1

Cysteine 52 of Arf-GAP domain and FG repeat-containing protein 1

A redox-regulated disulphide may form within Arf-GAP domain and FG repeat-containing protein 1 between cysteines 29 and 52.

Details

Redox score ?
72
PDB code
2olm
Structure name
arfgap domain of hiv-1 rev binding protein
Structure deposition date
2007-01-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
74
Minimum pKa ?
nan
% buried
nan
Peptide accession
P52594
Residue number A
29
Residue number B
52
Peptide name
Arf-GAP domain and FG repeat-containing protein 1

Ligandability

Cysteine 29 of Arf-GAP domain and FG repeat-containing protein 1

Cysteine 52 of Arf-GAP domain and FG repeat-containing protein 1

A redox-regulated disulphide may form within Arf-GAP domain and FG repeat-containing protein 1 between cysteines 29 and 32.

Details

Redox score ?
72
PDB code
2olm
Structure name
arfgap domain of hiv-1 rev binding protein
Structure deposition date
2007-01-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
P52594
Residue number A
29
Residue number B
32
Peptide name
Arf-GAP domain and FG repeat-containing protein 1

Ligandability

Cysteine 29 of Arf-GAP domain and FG repeat-containing protein 1

Cysteine 32 of Arf-GAP domain and FG repeat-containing protein 1

A redox-regulated disulphide may form within Arf-GAP domain and FG repeat-containing protein 1 between cysteines 32 and 49.

Details

Redox score ?
71
PDB code
2olm
Structure name
arfgap domain of hiv-1 rev binding protein
Structure deposition date
2007-01-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
P52594
Residue number A
32
Residue number B
49
Peptide name
Arf-GAP domain and FG repeat-containing protein 1

Ligandability

Cysteine 32 of Arf-GAP domain and FG repeat-containing protein 1

Cysteine 49 of Arf-GAP domain and FG repeat-containing protein 1

A redox-regulated disulphide may form within Arf-GAP domain and FG repeat-containing protein 1 between cysteines 49 and 52.

Details

Redox score ?
71
PDB code
2olm
Structure name
arfgap domain of hiv-1 rev binding protein
Structure deposition date
2007-01-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide accession
P52594
Residue number A
49
Residue number B
52
Peptide name
Arf-GAP domain and FG repeat-containing protein 1

Ligandability

Cysteine 49 of Arf-GAP domain and FG repeat-containing protein 1

Cysteine 52 of Arf-GAP domain and FG repeat-containing protein 1

A redox-regulated disulphide may form within Arf-GAP domain and FG repeat-containing protein 1 between cysteines 29 and 49.

Details

Redox score ?
70
PDB code
2olm
Structure name
arfgap domain of hiv-1 rev binding protein
Structure deposition date
2007-01-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P52594
Residue number A
29
Residue number B
49
Peptide name
Arf-GAP domain and FG repeat-containing protein 1

Ligandability

Cysteine 29 of Arf-GAP domain and FG repeat-containing protein 1

Cysteine 49 of Arf-GAP domain and FG repeat-containing protein 1

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