Signal transducer and activator of transcription 2

Intramolecular

A redox-regulated disulphide may form within Signal transducer and activator of transcription 2 between cysteines 246 and 323. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

6ux2

Structure name

crystal structure of zikv rdrp in complex with stat2

Structure deposition date

2019-11-06

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

P52630

Residue number A

246

Residue number B

323

Peptide name

Signal transducer and activator of transcription 2

Ligandability

Cysteine 246 of Signal transducer and activator of transcription 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.