a tool for identifying drug-targetable redox-active disulphides

Kinesin-like protein KIF11

Intramolecular

Cysteine 25 and cysteine 43

A redox-regulated disulphide may form within Kinesin-like protein KIF11 between cysteines 25 and 43.

Details

Redox score ?

78

PDB code

Structure name

eg5(wt) complex

Structure deposition date

2013-07-15

Thiol separation (Å)

3

Half-sphere exposure sum ?

77

Minimum pK_a ?

7

% buried

62

Peptide accession

Residue number A

25

Residue number B

43

Peptide name

Kinesin-like protein KIF11

Ligandability

Cysteine 25 of Kinesin-like protein KIF11

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 43 of Kinesin-like protein KIF11

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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