RNA-binding protein 5
Intramolecular
Cysteine 201 and cysteine 204
Cysteine 187 and cysteine 201
Cysteine 190 and cysteine 201
Cysteine 190 and cysteine 204
Cysteine 187 and cysteine 190
Cysteine 187 and cysteine 204
Cysteine 190 and cysteine 191
Cysteine 187 and cysteine 191
Cysteine 191 and cysteine 201
Cysteine 191 and cysteine 204
7pcv A 110 A 113
A redox-regulated disulphide may form within RNA-binding protein 5 between cysteines 201 and 204 (110 and 113 respectively in this structure).
Details
Redox score ?
89
PDB code
7pcv
Structure name
crystal structure of rbm5 rrm1-zinc finger
Structure deposition date
2021-08-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
5
% buried
9
Peptide accession
P52756
Residue number A
201
Residue number B
204
Peptide name
RNA-binding protein 5
Ligandability
Cysteine 201 of RNA-binding protein 5
Cysteine 204 of RNA-binding protein 5
7pcv B 96 B 110
A redox-regulated disulphide may form within RNA-binding protein 5 between cysteines 187 and 201 (96 and 110 respectively in this structure).
Details
Redox score ?
88
PDB code
7pcv
Structure name
crystal structure of rbm5 rrm1-zinc finger
Structure deposition date
2021-08-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
59
Minimum pKa ?
5
% buried
22
Peptide accession
P52756
Residue number A
187
Residue number B
201
Peptide name
RNA-binding protein 5
Ligandability
Cysteine 187 of RNA-binding protein 5
Cysteine 201 of RNA-binding protein 5
7pcv B 99 B 110
A redox-regulated disulphide may form within RNA-binding protein 5 between cysteines 190 and 201 (99 and 110 respectively in this structure).
Details
Redox score ?
87
PDB code
7pcv
Structure name
crystal structure of rbm5 rrm1-zinc finger
Structure deposition date
2021-08-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
56
Minimum pKa ?
5
% buried
6
Peptide accession
P52756
Residue number A
190
Residue number B
201
Peptide name
RNA-binding protein 5
Ligandability
Cysteine 190 of RNA-binding protein 5
Cysteine 201 of RNA-binding protein 5
7pcv A 99 A 113
A redox-regulated disulphide may form within RNA-binding protein 5 between cysteines 190 and 204 (99 and 113 respectively in this structure).
Details
Redox score ?
80
PDB code
7pcv
Structure name
crystal structure of rbm5 rrm1-zinc finger
Structure deposition date
2021-08-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
7
% buried
12
Peptide accession
P52756
Residue number A
190
Residue number B
204
Peptide name
RNA-binding protein 5
Ligandability
Cysteine 190 of RNA-binding protein 5
Cysteine 204 of RNA-binding protein 5
7pcv A 96 A 99
A redox-regulated disulphide may form within RNA-binding protein 5 between cysteines 187 and 190 (96 and 99 respectively in this structure).
Details
Redox score ?
80
PDB code
7pcv
Structure name
crystal structure of rbm5 rrm1-zinc finger
Structure deposition date
2021-08-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
63
Minimum pKa ?
7
% buried
22
Peptide accession
P52756
Residue number A
187
Residue number B
190
Peptide name
RNA-binding protein 5
Ligandability
Cysteine 187 of RNA-binding protein 5
Cysteine 190 of RNA-binding protein 5
7pcv B 96 B 113
A redox-regulated disulphide may form within RNA-binding protein 5 between cysteines 187 and 204 (96 and 113 respectively in this structure).
Details
Redox score ?
79
PDB code
7pcv
Structure name
crystal structure of rbm5 rrm1-zinc finger
Structure deposition date
2021-08-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
56
Minimum pKa ?
9
% buried
26
Peptide accession
P52756
Residue number A
187
Residue number B
204
Peptide name
RNA-binding protein 5
Ligandability
Cysteine 187 of RNA-binding protein 5
Cysteine 204 of RNA-binding protein 5
7pcv A 99 A 100
A redox-regulated disulphide may form within RNA-binding protein 5 between cysteines 190 and 191 (99 and 100 respectively in this structure).
Details
Redox score ?
60
PDB code
7pcv
Structure name
crystal structure of rbm5 rrm1-zinc finger
Structure deposition date
2021-08-04
Thiol separation (Å)
7
Half-sphere exposure sum ?
58
Minimum pKa ?
7
% buried
14
Peptide accession
P52756
Residue number A
190
Residue number B
191
Peptide name
RNA-binding protein 5
Ligandability
Cysteine 190 of RNA-binding protein 5
Cysteine 191 of RNA-binding protein 5
7pcv B 96 B 100
A redox-regulated disulphide may form within RNA-binding protein 5 between cysteines 187 and 191 (96 and 100 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
60
PDB code
7pcv
Structure name
crystal structure of rbm5 rrm1-zinc finger
Structure deposition date
2021-08-04
Thiol separation (Å)
7
Half-sphere exposure sum ?
52
Minimum pKa ?
9
% buried
18
Peptide accession
P52756
Residue number A
187
Residue number B
191
Peptide name
RNA-binding protein 5
Ligandability
Cysteine 187 of RNA-binding protein 5
Cysteine 191 of RNA-binding protein 5
7pcv A 100 A 110
A redox-regulated disulphide may form within RNA-binding protein 5 between cysteines 191 and 201 (100 and 110 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
7pcv
Structure name
crystal structure of rbm5 rrm1-zinc finger
Structure deposition date
2021-08-04
Thiol separation (Å)
10
Half-sphere exposure sum ?
53
Minimum pKa ?
5
% buried
11
Peptide accession
P52756
Residue number A
191
Residue number B
201
Peptide name
RNA-binding protein 5
Ligandability
Cysteine 191 of RNA-binding protein 5
Cysteine 201 of RNA-binding protein 5
7pcv B 100 B 113
A redox-regulated disulphide may form within RNA-binding protein 5 between cysteines 191 and 204 (100 and 113 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
7pcv
Structure name
crystal structure of rbm5 rrm1-zinc finger
Structure deposition date
2021-08-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
48
Minimum pKa ?
9
% buried
10
Peptide accession
P52756
Residue number A
191
Residue number B
204
Peptide name
RNA-binding protein 5
Ligandability
Cysteine 191 of RNA-binding protein 5
Cysteine 204 of RNA-binding protein 5
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