Hexokinase-3

A redox-regulated disulphide may form within Hexokinase-3 between cysteines 671 and 678. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

3hm8

Structure name

crystal structure of the c-terminal hexokinase domain of human hk3

Structure deposition date

2009-05-28

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

P52790

Residue number A

671

Residue number B

678

Peptide name

Hexokinase-3

Ligandability

Cysteine 671 of Hexokinase-3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 678 of Hexokinase-3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Hexokinase-3 between cysteines 678 and 691. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

3hm8

Structure name

crystal structure of the c-terminal hexokinase domain of human hk3

Structure deposition date

2009-05-28

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

P52790

Residue number A

678

Residue number B

691

Peptide name

Hexokinase-3

Ligandability

Cysteine 678 of Hexokinase-3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 691 of Hexokinase-3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Hexokinase-3 between cysteines 678 and 710. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?