a tool for identifying drug-targetable redox-active disulphides

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

Intramolecular

Cysteine 818 and cysteine 828

A redox-regulated disulphide may form within Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 between cysteines 818 and 828.

Details

Redox score ?

84

PDB code

Structure name

the sulfotransferase domain of human haparin sulfate n-deacetylase/n- sulfotransferase

Structure deposition date

1998-09-07

Thiol separation (Å)

2

Half-sphere exposure sum ?

63

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

818

Residue number B

828

Peptide name

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

Ligandability

Cysteine 818 of Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 828 of Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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