Serine/threonine-protein phosphatase 5

Intramolecular

A redox-regulated disulphide may form within Serine/threonine-protein phosphatase 5 between cysteines 382 and 404. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

5ui1

Structure name

crystal structure of human protein phosphatase 5c (pp5c) in complex with a triazole inhibitor

Structure deposition date

2017-01-12

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

P53041

Residue number A

382

Residue number B

404

Peptide name

Serine/threonine-protein phosphatase 5

Ligandability

Cysteine 382 of Serine/threonine-protein phosphatase 5

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 404 of Serine/threonine-protein phosphatase 5

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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