a tool for identifying drug-targetable redox-active disulphides

Beta-crystallin A4

Intramolecular

Cysteine 99 and cysteine 166

A redox-regulated disulphide may form within Beta-crystallin A4 between cysteines 99 and 166.

Details

Redox score ?

81

PDB code

Structure name

crystal structure of human beta-crystallin a4 (cryba4)

Structure deposition date

2010-02-24

Thiol separation (Å)

2

Half-sphere exposure sum ?

64

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

99

Residue number B

166

Peptide name

Beta-crystallin A4

Ligandability

Cysteine 99 of Beta-crystallin A4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 166 of Beta-crystallin A4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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