a tool for identifying drug-targetable redox-active disulphides

Adenylate kinase 2, mitochondrial

Intramolecular

Cysteine 42 and cysteine 92 L

A redox-regulated disulphide may form within Adenylate kinase 2, mitochondrial between cysteines 42 and 92.

Details

Redox score ?

83

PDB code

Structure name

structure of human adenylate kinase 2

Structure deposition date

2005-12-15

Thiol separation (Å)

2

Half-sphere exposure sum ?

60

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

42

Residue number B

92

Peptide name

Adenylate kinase 2, mitochondrial

Ligandability

Cysteine 42 of Adenylate kinase 2, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 92 of Adenylate kinase 2, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

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