C-C motif chemokine 18
Intermolecular
Cysteine 30 and cysteine 30
Intramolecular
Cysteine 30 and cysteine 54
Cysteine 31 and cysteine 70
Cysteine 31 and cysteine 54
Cysteine 54 and cysteine 70
Cysteine 30 and cysteine 31
Cysteine 30 and cysteine 70
4mhe A 11 D 11
A redox-regulated disulphide may form between two units of C-C motif chemokine 18 at cysteines 30 and 30 (11 and 11 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
4mhe
Structure name
crystal structure of cc-chemokine 18
Structure deposition date
2013-08-29
Thiol separation (Å)
9
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-C motif chemokine 18
Peptide B name
C-C motif chemokine 18
Peptide A accession
P55774
Peptide B accession
P55774
Peptide A residue number
30
Peptide B residue number
30
Ligandability
4mhe A 11 A 35
A redox-regulated disulphide may form within C-C motif chemokine 18 between cysteines 30 and 54 (11 and 35 respectively in this structure).
Details
Redox score ?
85
PDB code
4mhe
Structure name
crystal structure of cc-chemokine 18
Structure deposition date
2013-08-29
Thiol separation (Å)
2
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55774
Residue number A
30
Residue number B
54
Peptide name
C-C motif chemokine 18
Ligandability
Cysteine 30 of C-C motif chemokine 18
Cysteine 54 of C-C motif chemokine 18
4mhe D 12 D 51
A redox-regulated disulphide may form within C-C motif chemokine 18 between cysteines 31 and 70 (12 and 51 respectively in this structure).
Details
Redox score ?
80
PDB code
4mhe
Structure name
crystal structure of cc-chemokine 18
Structure deposition date
2013-08-29
Thiol separation (Å)
2
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55774
Residue number A
31
Residue number B
70
Peptide name
C-C motif chemokine 18
Ligandability
Cysteine 31 of C-C motif chemokine 18
Cysteine 70 of C-C motif chemokine 18
4mhe D 12 D 35
A redox-regulated disulphide may form within C-C motif chemokine 18 between cysteines 31 and 54 (12 and 35 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
56
PDB code
4mhe
Structure name
crystal structure of cc-chemokine 18
Structure deposition date
2013-08-29
Thiol separation (Å)
7
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55774
Residue number A
31
Residue number B
54
Peptide name
C-C motif chemokine 18
Ligandability
Cysteine 31 of C-C motif chemokine 18
Cysteine 54 of C-C motif chemokine 18
4mhe D 35 D 51
A redox-regulated disulphide may form within C-C motif chemokine 18 between cysteines 54 and 70 (35 and 51 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
4mhe
Structure name
crystal structure of cc-chemokine 18
Structure deposition date
2013-08-29
Thiol separation (Å)
9
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55774
Residue number A
54
Residue number B
70
Peptide name
C-C motif chemokine 18
Ligandability
Cysteine 54 of C-C motif chemokine 18
Cysteine 70 of C-C motif chemokine 18
4mhe D 11 D 12
A redox-regulated disulphide may form within C-C motif chemokine 18 between cysteines 30 and 31 (11 and 12 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
4mhe
Structure name
crystal structure of cc-chemokine 18
Structure deposition date
2013-08-29
Thiol separation (Å)
7
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55774
Residue number A
30
Residue number B
31
Peptide name
C-C motif chemokine 18
Ligandability
Cysteine 30 of C-C motif chemokine 18
Cysteine 31 of C-C motif chemokine 18
4mhe B 11 B 51
A redox-regulated disulphide may form within C-C motif chemokine 18 between cysteines 30 and 70 (11 and 51 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
4mhe
Structure name
crystal structure of cc-chemokine 18
Structure deposition date
2013-08-29
Thiol separation (Å)
8
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide accession
P55774
Residue number A
30
Residue number B
70
Peptide name
C-C motif chemokine 18
Ligandability
Cysteine 30 of C-C motif chemokine 18
Cysteine 70 of C-C motif chemokine 18
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