C-terminal-binding protein 2

Intermolecular

Intramolecular

A redox-regulated disulphide may form between two units of C-terminal-binding protein 2 at cysteines 140 and 140. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

2ome

Structure name

crystal structure of human ctbp2 dehydrogenase complexed with nad(h)

Structure deposition date

2007-01-22

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide A name

C-terminal-binding protein 2

Peptide B name

C-terminal-binding protein 2

Peptide A accession

P56545

Peptide B accession

P56545

Peptide A residue number

140

Peptide B residue number

140

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within C-terminal-binding protein 2 between cysteines 124 and 356.

Details

Redox score ?

PDB code

2ome

Structure name

crystal structure of human ctbp2 dehydrogenase complexed with nad(h)

Structure deposition date

2007-01-22

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

P56545

Residue number A

124

Residue number B

356

Peptide name

C-terminal-binding protein 2

Ligandability

Cysteine 124 of C-terminal-binding protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 356 of C-terminal-binding protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within C-terminal-binding protein 2 between cysteines 44 and 60. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?