ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Peroxisomal biogenesis factor 3

Intramolecular
Cysteine 123 and cysteine 283
A redox-regulated disulphide may form within Peroxisomal biogenesis factor 3 between cysteines 123 and 283. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
56
PDB code
3mk4
Structure name
x-ray structure of human pex3 in complex with a pex19 derived peptide
Structure deposition date
2010-04-14
Thiol separation (Å)
5
Half-sphere exposure sum ?
76
Minimum pKa ?
12
% buried
89
Peptide accession
P56589
Residue number A
123
Residue number B
283
Peptide name
Peroxisomal biogenesis factor 3

Ligandability

Cysteine 123 of Peroxisomal biogenesis factor 3

Cysteine 283 of Peroxisomal biogenesis factor 3

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