ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Ras-related protein Rab-38

Intramolecular
Cysteine 147 and cysteine 172
A redox-regulated disulphide may form within Ras-related protein Rab-38 between cysteines 147 and 172. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
36
PDB code
6hdu
Structure name
crystal structure of human rab38 in complex with gtp
Structure deposition date
2018-08-19
Thiol separation (Å)
10
Half-sphere exposure sum ?
58
Minimum pKa ?
10
% buried
56
Peptide accession
P57729
Residue number A
147
Residue number B
172
Peptide name
Ras-related protein Rab-38

Ligandability

Cysteine 147 of Ras-related protein Rab-38

Cysteine 172 of Ras-related protein Rab-38

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