ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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NACHT, LRR and PYD domains-containing protein 12

Intermolecular
Cysteine 11 and cysteine 11
A redox-regulated disulphide may form between two units of NACHT, LRR and PYD domains-containing protein 12 at cysteines 11 and 11 (378 and 378 respectively in this structure).

Details

Redox score ?
79
PDB code
4xhs
Structure name
crystal structure of human nlrp12 pyd domain and implication in homotypic interaction
Structure deposition date
2015-01-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide A name
NACHT, LRR and PYD domains-containing protein 12
Peptide B name
NACHT, LRR and PYD domains-containing protein 12
Peptide A accession
P59046
Peptide B accession
P59046
Peptide A residue number
11
Peptide B residue number
11

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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