ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Taste receptor type 2 member 46

Intramolecular
Cysteine 200 and cysteine 203
A redox-regulated disulphide may form within Taste receptor type 2 member 46 between cysteines 200 and 203. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
57
PDB code
7xp5
Structure name
cryo-em structure of a class t gpcr in ligand-free state
Structure deposition date
2022-05-03
Thiol separation (Å)
7
Half-sphere exposure sum ?
45
Minimum pKa ?
9
% buried
8
Peptide accession
P59540
Residue number A
200
Residue number B
203
Peptide name
Taste receptor type 2 member 46

Ligandability

Cysteine 200 of Taste receptor type 2 member 46

Cysteine 203 of Taste receptor type 2 member 46

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