Eukaryotic initiation factor 4A-I

Intramolecular

A redox-regulated disulphide may form within Eukaryotic initiation factor 4A-I between cysteines 131 and 134. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

7ppz

Structure name

crystal structure of the burkholderia lethal factor 1 (blf1) c94s inactive mutant in complex with human eif4a - crystal form a

Structure deposition date

2021-09-15

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

P60842

Residue number A

131

Residue number B

134

Peptide name

Eukaryotic initiation factor 4A-I

Ligandability

Cysteine 131 of Eukaryotic initiation factor 4A-I

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 134 of Eukaryotic initiation factor 4A-I

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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