a tool for identifying drug-targetable redox-active disulphides

Ras-related protein Rab-14

Intramolecular

Cysteine 26 and cysteine 40

A redox-regulated disulphide may form within Ras-related protein Rab-14 between cysteines 26 and 40.

Details

Redox score ?

86

PDB code

Structure name

structure of rab14 in complex with rab-coupling protein (rcp)

Structure deposition date

2014-04-25

Thiol separation (Å)

2

Half-sphere exposure sum ?

60

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

26

Residue number B

40

Peptide name

Ras-related protein Rab-14

Ligandability

Cysteine 26 of Ras-related protein Rab-14

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 40 of Ras-related protein Rab-14

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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