ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

40S ribosomal protein S3a

Intramolecular
Cysteine 139 and cysteine 201 L
A redox-regulated disulphide may form within 40S ribosomal protein S3a between cysteines 139 and 201. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
41
PDB code
7k5i
Structure name
sars-cov-2 nsp1 in complex with human 40s ribosome
Structure deposition date
2020-09-16
Thiol separation (Å)
9
Half-sphere exposure sum ?
70
Minimum pKa ?
11
% buried
88
Peptide accession
P61247
Residue number A
139
Residue number B
201
Peptide name
40S ribosomal protein S3a

Ligandability

Cysteine 139 of 40S ribosomal protein S3a

Cysteine 201 of 40S ribosomal protein S3a

If this tool was useful for finding a disulphide, please cite: