Insulin gene enhancer protein ISL-1
Intramolecular
Cysteine 79 and cysteine 82
Cysteine 17 and cysteine 20
Cysteine 17 and cysteine 42
Cysteine 45 and cysteine 48
Cysteine 107 and cysteine 110
Cysteine 107 and cysteine 129
Cysteine 79 and cysteine 104
Cysteine 45 and cysteine 67
Cysteine 20 and cysteine 42
Cysteine 110 and cysteine 129
More...Cysteine 48 and cysteine 67
Cysteine 82 and cysteine 104
Cysteine 45 and cysteine 17
2rgt B 93 B 96
A redox-regulated disulphide may form within Insulin gene enhancer protein ISL-1 between cysteines 79 and 82 (93 and 96 respectively in this structure).
Details
Redox score ?
91
PDB code
2rgt
Structure name
crystal structure of lhx3 lim domains 1 and 2 with the binding domain of isl1
Structure deposition date
2007-10-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
1
% buried
44
Peptide accession
P61372
Residue number A
79
Residue number B
82
Peptide name
Insulin gene enhancer protein ISL-1
Ligandability
Cysteine 79 of Insulin gene enhancer protein ISL-1
Cysteine 82 of Insulin gene enhancer protein ISL-1
2rgt B 34 B 37
A redox-regulated disulphide may form within Insulin gene enhancer protein ISL-1 between cysteines 17 and 20 (34 and 37 respectively in this structure).
Details
Redox score ?
86
PDB code
2rgt
Structure name
crystal structure of lhx3 lim domains 1 and 2 with the binding domain of isl1
Structure deposition date
2007-10-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
43
Minimum pKa ?
6
% buried
12
Peptide accession
P61372
Residue number A
17
Residue number B
20
Peptide name
Insulin gene enhancer protein ISL-1
Ligandability
Cysteine 17 of Insulin gene enhancer protein ISL-1
Cysteine 20 of Insulin gene enhancer protein ISL-1
2rgt A 34 A 58
A redox-regulated disulphide may form within Insulin gene enhancer protein ISL-1 between cysteines 17 and 42 (34 and 58 respectively in this structure).
Details
Redox score ?
85
PDB code
2rgt
Structure name
crystal structure of lhx3 lim domains 1 and 2 with the binding domain of isl1
Structure deposition date
2007-10-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
6
% buried
3
Peptide accession
P61372
Residue number A
17
Residue number B
42
Peptide name
Insulin gene enhancer protein ISL-1
Ligandability
Cysteine 17 of Insulin gene enhancer protein ISL-1
Cysteine 42 of Insulin gene enhancer protein ISL-1
2rgt A 61 A 64
A redox-regulated disulphide may form within Insulin gene enhancer protein ISL-1 between cysteines 45 and 48 (61 and 64 respectively in this structure).
Details
Redox score ?
84
PDB code
2rgt
Structure name
crystal structure of lhx3 lim domains 1 and 2 with the binding domain of isl1
Structure deposition date
2007-10-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
7
% buried
4
Peptide accession
P61372
Residue number A
45
Residue number B
48
Peptide name
Insulin gene enhancer protein ISL-1
Ligandability
Cysteine 45 of Insulin gene enhancer protein ISL-1
Cysteine 48 of Insulin gene enhancer protein ISL-1
2rgt B 121 B 124
A redox-regulated disulphide may form within Insulin gene enhancer protein ISL-1 between cysteines 107 and 110 (121 and 124 respectively in this structure).
Details
Redox score ?
82
PDB code
2rgt
Structure name
crystal structure of lhx3 lim domains 1 and 2 with the binding domain of isl1
Structure deposition date
2007-10-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
7
% buried
11
Peptide accession
P61372
Residue number A
107
Residue number B
110
Peptide name
Insulin gene enhancer protein ISL-1
Ligandability
Cysteine 107 of Insulin gene enhancer protein ISL-1
Cysteine 110 of Insulin gene enhancer protein ISL-1
2rgt A 121 A 144
A redox-regulated disulphide may form within Insulin gene enhancer protein ISL-1 between cysteines 107 and 129 (121 and 144 respectively in this structure).
Details
Redox score ?
81
PDB code
2rgt
Structure name
crystal structure of lhx3 lim domains 1 and 2 with the binding domain of isl1
Structure deposition date
2007-10-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
66
Minimum pKa ?
7
% buried
16
Peptide accession
P61372
Residue number A
107
Residue number B
129
Peptide name
Insulin gene enhancer protein ISL-1
Ligandability
Cysteine 107 of Insulin gene enhancer protein ISL-1
Cysteine 129 of Insulin gene enhancer protein ISL-1
2rgt A 93 A 118
A redox-regulated disulphide may form within Insulin gene enhancer protein ISL-1 between cysteines 79 and 104 (93 and 118 respectively in this structure).
Details
Redox score ?
80
PDB code
2rgt
Structure name
crystal structure of lhx3 lim domains 1 and 2 with the binding domain of isl1
Structure deposition date
2007-10-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
63
Minimum pKa ?
7
% buried
28
Peptide accession
P61372
Residue number A
79
Residue number B
104
Peptide name
Insulin gene enhancer protein ISL-1
Ligandability
Cysteine 79 of Insulin gene enhancer protein ISL-1
Cysteine 104 of Insulin gene enhancer protein ISL-1
2rgt B 61 B 81
A redox-regulated disulphide may form within Insulin gene enhancer protein ISL-1 between cysteines 45 and 67 (61 and 81 respectively in this structure).
Details
Redox score ?
78
PDB code
2rgt
Structure name
crystal structure of lhx3 lim domains 1 and 2 with the binding domain of isl1
Structure deposition date
2007-10-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
7
% buried
12
Peptide accession
P61372
Residue number A
45
Residue number B
67
Peptide name
Insulin gene enhancer protein ISL-1
Ligandability
Cysteine 45 of Insulin gene enhancer protein ISL-1
Cysteine 67 of Insulin gene enhancer protein ISL-1
2rgt A 37 A 58
A redox-regulated disulphide may form within Insulin gene enhancer protein ISL-1 between cysteines 20 and 42 (37 and 58 respectively in this structure).
Details
Redox score ?
77
PDB code
2rgt
Structure name
crystal structure of lhx3 lim domains 1 and 2 with the binding domain of isl1
Structure deposition date
2007-10-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
9
% buried
2
Peptide accession
P61372
Residue number A
20
Residue number B
42
Peptide name
Insulin gene enhancer protein ISL-1
Ligandability
Cysteine 20 of Insulin gene enhancer protein ISL-1
Cysteine 42 of Insulin gene enhancer protein ISL-1
2rgt A 124 A 144
A redox-regulated disulphide may form within Insulin gene enhancer protein ISL-1 between cysteines 110 and 129 (124 and 144 respectively in this structure).
Details
Redox score ?
75
PDB code
2rgt
Structure name
crystal structure of lhx3 lim domains 1 and 2 with the binding domain of isl1
Structure deposition date
2007-10-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
9
% buried
5
Peptide accession
P61372
Residue number A
110
Residue number B
129
Peptide name
Insulin gene enhancer protein ISL-1
Ligandability
Cysteine 110 of Insulin gene enhancer protein ISL-1
Cysteine 129 of Insulin gene enhancer protein ISL-1
2rgt B 64 B 81
A redox-regulated disulphide may form within Insulin gene enhancer protein ISL-1 between cysteines 48 and 67 (64 and 81 respectively in this structure).
Details
Redox score ?
74
PDB code
2rgt
Structure name
crystal structure of lhx3 lim domains 1 and 2 with the binding domain of isl1
Structure deposition date
2007-10-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
51
Minimum pKa ?
9
% buried
6
Peptide accession
P61372
Residue number A
48
Residue number B
67
Peptide name
Insulin gene enhancer protein ISL-1
Ligandability
Cysteine 48 of Insulin gene enhancer protein ISL-1
Cysteine 67 of Insulin gene enhancer protein ISL-1
2rgt B 96 B 118
A redox-regulated disulphide may form within Insulin gene enhancer protein ISL-1 between cysteines 82 and 104 (96 and 118 respectively in this structure).
Details
Redox score ?
71
PDB code
2rgt
Structure name
crystal structure of lhx3 lim domains 1 and 2 with the binding domain of isl1
Structure deposition date
2007-10-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
9
% buried
42
Peptide accession
P61372
Residue number A
82
Residue number B
104
Peptide name
Insulin gene enhancer protein ISL-1
Ligandability
Cysteine 82 of Insulin gene enhancer protein ISL-1
Cysteine 104 of Insulin gene enhancer protein ISL-1
2rgt A 61 A 72
A redox-regulated disulphide may form within Insulin gene enhancer protein ISL-1 between cysteines 45 and 17 (61 and 72 respectively in this structure).
Details
Redox score ?
nan
PDB code
2rgt
Structure name
crystal structure of lhx3 lim domains 1 and 2 with the binding domain of isl1
Structure deposition date
2007-10-05
Thiol separation (Å)
10
Half-sphere exposure sum ?
52
Minimum pKa ?
7
% buried
16
Peptide accession
P61372
Residue number A
45
Residue number B
17
Peptide name
Insulin gene enhancer protein ISL-1
Ligandability
Cysteine 45 of Insulin gene enhancer protein ISL-1
Cysteine 17 of Insulin gene enhancer protein ISL-1
Uncertain whether structure cysteine 72 has been assigned to correct residue.
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