ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Neuronal calcium sensor 1

Intermolecular
Cysteine 38 and cysteine 38
A redox-regulated disulphide may form between two units of Neuronal calcium sensor 1 at cysteines 38 and 38. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
59
PDB code
4yru
Structure name
crystal structure of c-terminally truncated neuronal calcium sensor (ncs-1) from rattus norvegicus
Structure deposition date
2015-03-15
Thiol separation (Å)
7
Half-sphere exposure sum ?
61
Minimum pKa ?
9
% buried
74
Peptide A name
Neuronal calcium sensor 1
Peptide B name
Neuronal calcium sensor 1
Peptide A accession
P62168
Peptide B accession
P62168
Peptide A residue number
38
Peptide B residue number
38

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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