40S ribosomal protein S29
Intramolecular
Cysteine 21 and cysteine 24
Cysteine 21 and cysteine 39
Cysteine 24 and cysteine 39
Cysteine 39 and cysteine 42
Cysteine 24 and cysteine 42
Cysteine 21 and cysteine 42
6g5h d 21 d 24
A redox-regulated disulphide may form within 40S ribosomal protein S29 between cysteines 21 and 24.
Details
Redox score ?
89
PDB code
6g5h
Structure name
cryo-em structure of a late human pre-40s ribosomal subunit - mature
Structure deposition date
2018-03-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
0
% buried
100
Peptide accession
P62273
Residue number A
21
Residue number B
24
Peptide name
40S ribosomal protein S29
Ligandability
Cysteine 21 of 40S ribosomal protein S29
Cysteine 24 of 40S ribosomal protein S29
7k5i d 21 d 39
A redox-regulated disulphide may form within 40S ribosomal protein S29 between cysteines 21 and 39.
Details
Redox score ?
82
PDB code
7k5i
Structure name
sars-cov-2 nsp1 in complex with human 40s ribosome
Structure deposition date
2020-09-16
Thiol separation (Å)
4
Half-sphere exposure sum ?
56
Minimum pKa ?
5
% buried
nan
Peptide accession
P62273
Residue number A
21
Residue number B
39
Peptide name
40S ribosomal protein S29
Ligandability
Cysteine 21 of 40S ribosomal protein S29
Cysteine 39 of 40S ribosomal protein S29
7k5i d 24 d 39
A redox-regulated disulphide may form within 40S ribosomal protein S29 between cysteines 24 and 39.
Details
Redox score ?
76
PDB code
7k5i
Structure name
sars-cov-2 nsp1 in complex with human 40s ribosome
Structure deposition date
2020-09-16
Thiol separation (Å)
4
Half-sphere exposure sum ?
54
Minimum pKa ?
5
% buried
99
Peptide accession
P62273
Residue number A
24
Residue number B
39
Peptide name
40S ribosomal protein S29
Ligandability
Cysteine 24 of 40S ribosomal protein S29
Cysteine 39 of 40S ribosomal protein S29
5flx d 39 d 42
A redox-regulated disulphide may form within 40S ribosomal protein S29 between cysteines 39 and 42.
Details
Redox score ?
75
PDB code
5flx
Structure name
mammalian 40s hcv-ires complex
Structure deposition date
2015-10-28
Thiol separation (Å)
3
Half-sphere exposure sum ?
57
Minimum pKa ?
7
% buried
100
Peptide accession
P62273
Residue number A
39
Residue number B
42
Peptide name
40S ribosomal protein S29
Ligandability
Cysteine 39 of 40S ribosomal protein S29
Cysteine 42 of 40S ribosomal protein S29
6g5i d 24 d 42
A redox-regulated disulphide may form within 40S ribosomal protein S29 between cysteines 24 and 42. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
6g5i
Structure name
cryo-em structure of a late human pre-40s ribosomal subunit - state r
Structure deposition date
2018-03-29
Thiol separation (Å)
4
Half-sphere exposure sum ?
54
Minimum pKa ?
16
% buried
100
Peptide accession
P62273
Residue number A
24
Residue number B
42
Peptide name
40S ribosomal protein S29
Ligandability
Cysteine 24 of 40S ribosomal protein S29
Cysteine 42 of 40S ribosomal protein S29
5a2q d 21 d 42
A redox-regulated disulphide may form within 40S ribosomal protein S29 between cysteines 21 and 42. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
5a2q
Structure name
structure of the hcv ires bound to the human ribosome
Structure deposition date
2015-05-21
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
25
% buried
nan
Peptide accession
P62273
Residue number A
21
Residue number B
42
Peptide name
40S ribosomal protein S29
Ligandability
Cysteine 21 of 40S ribosomal protein S29
Cysteine 42 of 40S ribosomal protein S29
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