26S proteasome regulatory subunit 10B

Intramolecular

A redox-regulated disulphide may form within 26S proteasome regulatory subunit 10B between cysteines 193 and 228. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

5m32

Structure name

human 26s proteasome in complex with oprozomib

Structure deposition date

2016-10-14

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

P62333

Residue number A

193

Residue number B

228

Peptide name

26S proteasome regulatory subunit 10B

Ligandability

Cysteine 193 of 26S proteasome regulatory subunit 10B

Ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Ligandable in the dataset of Backus et al.

Ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 228 of 26S proteasome regulatory subunit 10B

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

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