ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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GTP-binding nuclear protein Ran

Intramolecular
Cysteine 85 and cysteine 112 L
A redox-regulated disulphide may form within GTP-binding nuclear protein Ran between cysteines 85 and 112. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
35
PDB code
1a2k
Structure name
gdpran-ntf2 complex
Structure deposition date
1998-01-06
Thiol separation (Å)
10
Half-sphere exposure sum ?
69
Minimum pKa ?
10
% buried
69
Peptide accession
P62825
Residue number A
85
Residue number B
112
Peptide name
GTP-binding nuclear protein Ran

Ligandability

Cysteine 85 of GTP-binding nuclear protein Ran

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 112 of GTP-binding nuclear protein Ran

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

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