ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Ras-related protein Rap-1A

Intramolecular
Cysteine 139 and cysteine 141
A redox-regulated disulphide may form within Ras-related protein Rap-1A between cysteines 139 and 141. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
47
PDB code
1c1y
Structure name
crystal structure of rap
Structure deposition date
1999-07-22
Thiol separation (Å)
9
Half-sphere exposure sum ?
47
Minimum pKa ?
9
% buried
38
Peptide accession
P62834
Residue number A
139
Residue number B
141
Peptide name
Ras-related protein Rap-1A

Ligandability

Cysteine 139 of Ras-related protein Rap-1A

Cysteine 141 of Ras-related protein Rap-1A

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