40S ribosomal protein S26
Intramolecular
Cysteine 26 and cysteine 77
Cysteine 23 and cysteine 26
Cysteine 23 and cysteine 74
Cysteine 26 and cysteine 74
Cysteine 74 and cysteine 77
Cysteine 26 and cysteine 29
Cysteine 23 and cysteine 77
Cysteine 23 and cysteine 29
7syh b 26 b 77
A redox-regulated disulphide may form within 40S ribosomal protein S26 between cysteines 26 and 77.
Details
Redox score ?
84
PDB code
7syh
Structure name
structure of the hcv ires binding to the 40s ribosomal subunit, closed conformation
Structure deposition date
2021-11-25
Thiol separation (Å)
3
Half-sphere exposure sum ?
60
Minimum pKa ?
6
% buried
86
Peptide accession
P61251
Residue number A
26
Residue number B
77
Peptide name
40S ribosomal protein S26
Ligandability
Cysteine 26 of 40S ribosomal protein S26
Cysteine 77 of 40S ribosomal protein S26
7syh b 23 b 26
A redox-regulated disulphide may form within 40S ribosomal protein S26 between cysteines 23 and 26.
Details
Redox score ?
82
PDB code
7syh
Structure name
structure of the hcv ires binding to the 40s ribosomal subunit, closed conformation
Structure deposition date
2021-11-25
Thiol separation (Å)
3
Half-sphere exposure sum ?
71
Minimum pKa ?
6
% buried
nan
Peptide accession
P61251
Residue number A
23
Residue number B
26
Peptide name
40S ribosomal protein S26
Ligandability
Cysteine 23 of 40S ribosomal protein S26
Cysteine 26 of 40S ribosomal protein S26
7k5i a 23 a 74
A redox-regulated disulphide may form within 40S ribosomal protein S26 between cysteines 23 and 74.
Details
Redox score ?
81
PDB code
7k5i
Structure name
sars-cov-2 nsp1 in complex with human 40s ribosome
Structure deposition date
2020-09-16
Thiol separation (Å)
4
Half-sphere exposure sum ?
74
Minimum pKa ?
5
% buried
nan
Peptide accession
P62854
Residue number A
23
Residue number B
74
Peptide name
40S ribosomal protein S26
Ligandability
Cysteine 23 of 40S ribosomal protein S26
Cysteine 74 of 40S ribosomal protein S26
7syh b 26 b 74
A redox-regulated disulphide may form within 40S ribosomal protein S26 between cysteines 26 and 74.
Details
Redox score ?
80
PDB code
7syh
Structure name
structure of the hcv ires binding to the 40s ribosomal subunit, closed conformation
Structure deposition date
2021-11-25
Thiol separation (Å)
3
Half-sphere exposure sum ?
67
Minimum pKa ?
6
% buried
90
Peptide accession
P61251
Residue number A
26
Residue number B
74
Peptide name
40S ribosomal protein S26
Ligandability
Cysteine 26 of 40S ribosomal protein S26
Cysteine 74 of 40S ribosomal protein S26
7syh b 74 b 77
A redox-regulated disulphide may form within 40S ribosomal protein S26 between cysteines 74 and 77.
Details
Redox score ?
65
PDB code
7syh
Structure name
structure of the hcv ires binding to the 40s ribosomal subunit, closed conformation
Structure deposition date
2021-11-25
Thiol separation (Å)
3
Half-sphere exposure sum ?
65
Minimum pKa ?
15
% buried
84
Peptide accession
P61251
Residue number A
74
Residue number B
77
Peptide name
40S ribosomal protein S26
Ligandability
Cysteine 74 of 40S ribosomal protein S26
Cysteine 77 of 40S ribosomal protein S26
7syh b 26 b 29
A redox-regulated disulphide may form within 40S ribosomal protein S26 between cysteines 26 and 29. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
7syh
Structure name
structure of the hcv ires binding to the 40s ribosomal subunit, closed conformation
Structure deposition date
2021-11-25
Thiol separation (Å)
9
Half-sphere exposure sum ?
60
Minimum pKa ?
6
% buried
96
Peptide accession
P61251
Residue number A
26
Residue number B
29
Peptide name
40S ribosomal protein S26
Ligandability
Cysteine 26 of 40S ribosomal protein S26
Cysteine 29 of 40S ribosomal protein S26
7syh b 23 b 77
A redox-regulated disulphide may form within 40S ribosomal protein S26 between cysteines 23 and 77. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
7syh
Structure name
structure of the hcv ires binding to the 40s ribosomal subunit, closed conformation
Structure deposition date
2021-11-25
Thiol separation (Å)
4
Half-sphere exposure sum ?
69
Minimum pKa ?
23
% buried
nan
Peptide accession
P61251
Residue number A
23
Residue number B
77
Peptide name
40S ribosomal protein S26
Ligandability
Cysteine 23 of 40S ribosomal protein S26
Cysteine 77 of 40S ribosomal protein S26
5oa3 a 23 a 29
A redox-regulated disulphide may form within 40S ribosomal protein S26 between cysteines 23 and 29. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
5oa3
Structure name
human 40s-eif2d-re-initiation complex
Structure deposition date
2017-06-20
Thiol separation (Å)
10
Half-sphere exposure sum ?
67
Minimum pKa ?
7
% buried
nan
Peptide accession
P62854
Residue number A
23
Residue number B
29
Peptide name
40S ribosomal protein S26
Ligandability
Cysteine 23 of 40S ribosomal protein S26
Cysteine 29 of 40S ribosomal protein S26
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