ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Endogenous retrovirus group K member 24 Gag polyprotein

Intramolecular
Cysteine 488 and cysteine 513
A redox-regulated disulphide may form within Endogenous retrovirus group K member 24 Gag polyprotein between cysteines 488 and 513 (206 and 231 respectively in this structure).

Details

Redox score ?
77
PDB code
6ssl
Structure name
human endogenous retrovirus (hml2) mature capsid assembly, d6 capsule
Structure deposition date
2019-09-08
Thiol separation (Å)
4
Half-sphere exposure sum ?
58
Minimum pKa ?
10
% buried
23
Peptide accession
P63145
Residue number A
488
Residue number B
513
Peptide name
Endogenous retrovirus group K member 24 Gag polyprotein

Ligandability

Cysteine 488 of Endogenous retrovirus group K member 24 Gag polyprotein

Cysteine 513 of Endogenous retrovirus group K member 24 Gag polyprotein

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